Cellosaurus MCF7 Tet-Off advanced (CVCL_KU37)
| Cell line name | MCF7 Tet-Off advanced |
|---|---|
| Synonyms | MCF-7 Tet-Off advanced |
| Accession | CVCL_KU37 |
| Resource Identification Initiative | To cite this cell line use: MCF7 Tet-Off advanced (RRID:CVCL_KU37) |
| Comments | Population: Caucasian. Characteristics: Transfected with an advanced tetracycline transactivator (tTA2(S)-M2) protein, a fusion of a mutated E.coli tetR with the activation domain of HSV-1 VP16. Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P04483; Escherichia coli Tn10 tetR. Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P06492; Human herpesvirus 1 (HHV-1) VP16 (UL28) (Note=With p.Met1_Arg360del). Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175. |
| Sequence variations |
|
| Disease | Invasive breast carcinoma of no special type (NCIt: C4194) |
| Species of origin | Homo sapiens (Human) (NCBI Taxonomy: 9606) |
| Hierarchy | Parent: CVCL_0031 (MCF-7) |
| Sex of cell | Female |
| Age at sampling | 69Y |
| Category | Cancer cell line |
| Web pages | Provider; Takara Bio; 632109; https://www.takarabio.com/documents/Certificate%20of%20Analysis/632109/632109-051518.pdf |
| Cross-references | |
| Cell line databases/resources | cancercelllines; CVCL_KU37 |
| Encyclopedic resources | Wikidata; Q54904452 |
| Entry history | |
| Entry creation | 22-Aug-2017 |
| Last entry update | 14-Aug-2025 |
| Version number | 16 |