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Cellosaurus CellSensor LEF/TCF-bla SW480 (CVCL_KS03)

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Cell line name CellSensor LEF/TCF-bla SW480
Synonyms LEF/TCF-bla SW480; LEF/TCF-bla SW 480
Accession CVCL_KS03
Resource Identification Initiative To cite this cell line use: CellSensor LEF/TCF-bla SW480 (RRID:CVCL_KS03)
Comments Population: Caucasian.
Characteristics: Transfected with a plasmid containing a beta-lactamase reporter gene under control of beta-catenin/LEF/TCF binding elements.
Genetic integration: Method=Transfection; Gene=UniProtKB; P33967; Bacillus cereus Bsr.
Genetic integration: Method=Transfection; Gene=UniProtKB; P62593; Escherichia coli beta-lactamase bla (Note=With p.Met1_Phe22del, p.Ala23Met, p.Val82Ile and p.Met184Val).
Derived from site: In situ; Colon; UBERON=UBERON_0001155.
Sequence variations
  • Mutation; HGNC; HGNC:583; APC; Simple; p.Gln1338Ter (c.4012C>T); ClinVar=VCV000000801; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Val (c.35G>T); ClinVar=VCV000012583; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg273His (c.818G>A); ClinVar=VCV000012366; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Pro309Ser (c.925C>T); ClinVar=VCV000458575; Zygosity=Heterozygous (from parent cell line).
Disease Colon adenocarcinoma (NCIt: C4349)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0546 (SW480)
Sex of cell Male
Age at sampling 51Y
Category Cancer cell line
Web pages Provider; Thermo Fisher; K1675; https://www.thermofisher.com/order/catalog/product/K1675
Cross-references
Cell line databases/resources cancercelllines; CVCL_KS03
Encyclopedic resources Wikidata; Q54809199
Entry history
Entry creation22-Aug-2017
Last entry update14-Aug-2025
Version number17