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Cellosaurus U2OS FKHRL1-EGFP (CVCL_KA04)

[Text version]
Cell line name U2OS FKHRL1-EGFP
Synonyms FKHRL1_U2OS
Accession CVCL_KA04
Resource Identification Initiative To cite this cell line use: U2OS FKHRL1-EGFP (RRID:CVCL_KA04)
Comments Population: Caucasian.
Characteristics: Transfected with a fusion FOXO3-eGFP protein under the control of the CMV promoter.
Transfected with: HGNC; 3821; FOXO3.
Transfected with: UniProtKB; P42212; GFP (with p.Phe64Leu, p.Ser65Thr and p.His231Leu = EGFP).
Discontinued: Thermofisher/BioImage; Catalog number R04-009-02.
Derived from site: In situ; Bone, tibia; UBERON=UBERON_0000979.
Sequence variations
  • Mutation; HGNC; 9277; PPM1D; Simple; p.Arg458Ter (c.1372C>T); ClinVar=VCV002445214; Zygosity=Heterozygous (from parent cell line).
Disease Osteosarcoma (NCIt: C9145)
Osteosarcoma (ORDO: Orphanet_668)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0042 (U2OS)
Sex of cell Female
Age at sampling 15Y
Category Cancer cell line
Web pages http://tools.thermofisher.com/content/sfs/manuals/D03267~.pdf
Encyclopedic resources Wikidata; Q54973654
Entry history
Entry creation22-Aug-2017
Last entry update05-Oct-2023
Version number8