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Cellosaurus CC 49 (CVCL_K141)

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Cell line name CC 49
Synonyms CC-49; CC49
Accession CVCL_K141
Resource Identification Initiative To cite this cell line use: CC 49 (RRID:CVCL_K141)
Comments Group: Patented cell line.
Registration: International Depositary Authority, American Type Culture Collection (ATCC); HB-9459.
Biotechnology: The monoclonal antibody produced by this hybridoma is known as minretumomab and has been used in phase 1 clinical trials for the treatment of various cancers.
Monoclonal antibody isotype: IgG1, kappa.
Monoclonal antibody target: Human tumor-associated glycoprotein 72 (TAG-72) (CA72-4).
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Hierarchy Parent: CVCL_2155 (P3/NS1/1-Ag4.1)
Category Hybridoma
Publications

PubMed=3396010
Raffaella Muraro, Masahide Kuroki, David Wunderlich, Diane J. Poole, David Colcher, Ann Thor, John William Greiner, Jean F. Simpson, Alfredo Alberto Molinolo, Philip David Noguchi, Jeffrey Schlom;
Generation and characterization of B72.3 second generation monoclonal antibodies reactive with the tumor-associated glycoprotein 72 antigen.
Cancer Res. 48:4588-4596(1988)

Patent=US5512443
Jeffrey Schlom, David Colcher;
Second generation monoclonal antibodies having binding specificity to TAG-72 and human carcinomas and methods for employing the same.
Patent number US5512443, 30-Apr-1996

DOI=10.1089/hyb.1997.16.207
Pierre L. Triozzi;
CC49.
Hybridoma 16:207-207(1997)

Cross-references
Cell line collections (Providers) ATCC; HB-9459 - Discontinued
Cell line databases/resources CLO; CLO_0002214
Biological sample resources ABCD; ABCD_AJ342
Encyclopedic resources Wikidata; Q54808696
Entry history
Entry creation11-Feb-2013
Last entry update14-Aug-2025
Version number13