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Cellosaurus CBL-1 (CVCL_K136)

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Cell line name CBL-1
Synonyms CBL1
Accession CVCL_K136
Resource Identification Initiative To cite this cell line use: CBL-1 (RRID:CVCL_K136)
Comments Group: Patented cell line.
Registration: International Depositary Authority, American Type Culture Collection (ATCC); HB-8214.
Biotechnology: Was used to produce the monoclonal antibody gavilimomab (ABX-CBL) which was intended for use as an immunosuppressive biologic treatment of glucocorticoid-resistant graft versus host disease (Patent=US20070048305).
Monoclonal antibody isotype: IgM.
Monoclonal antibody target: UniProtKB; P35613; Human BSG/CD147.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Hierarchy Parent: CVCL_4032 (P3X63Ag8.653)
Category Hybridoma
Publications

PubMed=6208131; DOI=10.1089/hyb.1.1982.1.303
Ronald James Billing, John Wells, Diane Zettel, Paul Ichiro Terasaki;
Monoclonal and heteroantibody reacting with different antigens common to human blast cells and monocytes.
Hybridoma 1:303-311(1982)

Patent=US5330896
Ronald James Billing;
Monoclonal antibodies to an autocrine growth factor antigen that binds to activated lymphocytes and cancer cells.
Patent number US5330896, 19-Jul-1994

Patent=US20070048305
C. Geoffrey Davis, Russell W. Blacher, Jose Ramon Corvalan, Alan R. Culwell, Larry L. Green, Joanna Hales, Nancy Havrilla, Vladimir E. Ivanov, John A. Lipani, Qiang Liu, Richard F. Weber, Xiao-Dong Yang;
CD147 binding molecules as therapeutics.
Patent number US20070048305, 01-Mar-2007

Cross-references
Cell line collections (Providers) ATCC; HB-8214
Cell line databases/resources CLO; CLO_0002213
Biological sample resources ABCD; ABCD_AR015
Encyclopedic resources Wikidata; Q54808674
Entry history
Entry creation11-Feb-2013
Last entry update02-May-2024
Version number7