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Cellosaurus Bruce-4 (CVCL_K037)

[Text version]
Cell line name Bruce-4
Synonyms BRUCE-4; Bruce 4; Bruce4; BRUCE4; ES-Bruce4; EmbryoMax C57/BL6; CMTI-2
Accession CVCL_K037
Resource Identification Initiative To cite this cell line use: Bruce-4 (RRID:CVCL_K037)
Comments Part of: ENCODE project mouse cell lines.
Omics: Genomics; ChIP-seq; H3K27ac.
Omics: Genomics; ChIP-seq; H3K27me3.
Omics: Genomics; ChIP-seq; H3K36me3.
Omics: Genomics; ChIP-seq; H3K4me1.
Omics: Genomics; ChIP-seq; H3K4me3.
Omics: Genomics; ChIP-seq; H3K9ac.
Omics: Genomics; ChIP-seq; H3K9me3.
Omics: Variations; SNP array analysis.
Misspelling: CMT1-2; PubMed=25277546.
Derived from site: In situ; Blastocyst; UBERON=UBERON_0000358.
Cell type: Embryonic stem cell; CL=CL_0002322.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: C57BL/6.Cg-Thy1<a>.
Hierarchy Children:
CVCL_HE69 (SF-CMTI-2)
Sex of cell Male
Age at sampling Blastocyst stage
Category Embryonic stem cell
Web pages Provider; Michigan TCPS; -; https://medresearch.umich.edu/office-research/about-office-research/biomedical-research-core-facilities/transgenic-animal-model/transgenic-core-products-services
Publications

PubMed=8398989; DOI=10.1093/intimm/5.8.957
Frank Kontgen, Gabriele Suss, Colin Stewart, Michael Steinmetz, Horst Bluethmann;
Targeted disruption of the MHC class II Aa gene in C57BL/6 mice.
Int. Immunol. 5:957-964(1993)

PubMed=17828574; DOI=10.1007/s00335-007-9054-0
Elizabeth D. Hughes, Yun Yan Qu, Suzanne J. Genik, Robert H. Lyons, Christopher D. Pacheco, Andrew P. Lieberman, Linda Carol Samuelson, Igor O. Nasonkin, Sally Ann Camper, Margaret L. Van Keuren, Thomas Lee Saunders;
Genetic variation in C57BL/6 ES cell lines and genetic instability in the Bruce4 C57BL/6 ES cell line.
Mamm. Genome 18:549-558(2007)

PubMed=25277546; DOI=10.1186/1471-2164-15-847; PMCID=PMC4198738
John Paul Didion, Ryan J. Buus, Zohreh Naghashfar, David W. Threadgill, Herbert Carpenter Morse 3rd, Fernando Pardo-Manuel de Villena;
SNP array profiling of mouse cell lines identifies their strains of origin and reveals cross-contamination and widespread aneuploidy.
BMC Genomics 15:847.1-847.11(2014)

Cross-references
Cell line collections (Providers) Millipore; CMTI-2
Biological sample resources ENCODE; ENCBS250IKX
ENCODE; ENCBS359ENC
ENCODE; ENCBS551ZCI
ENCODE; ENCBS855UGJ
Encyclopedic resources Wikidata; Q54798320
Experimental variables resources EFO; EFO_0005483
Gene expression databases GEO; GSM769008
GEO; GSM769009
GEO; GSM769010
GEO; GSM918748
GEO; GSM918749
GEO; GSM918750
GEO; GSM1000089
GEO; GSM1000099
GEO; GSM1000109
GEO; GSM1000127
GEO; GSM1000147
Entry history
Entry creation11-Feb-2013
Last entry update10-Apr-2025
Version number15