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Cellosaurus MFD-1 (CVCL_JY36)

[Text version]
Cell line name MFD-1
Accession CVCL_JY36
Resource Identification Initiative To cite this cell line use: MFD-1 (RRID:CVCL_JY36)
Comments Omics: Genomics; Chromatin accessibility; ATAC-seq.
Omics: Transcriptomics; RNAseq.
Omics: Variations; SNP array analysis.
Derived from site: In situ; Esophagus; UBERON=UBERON_0001043.
Sequence variations
  • Mutation; HGNC; HGNC:40; ABCB1; Simple; p.Glu406Asp (c.1218T>G); Zygosity=Heterozygous (PubMed=27600491).
  • Mutation; HGNC; HGNC:40; ABCB1; Simple; p.Phe904Val (c.2710T>G); Zygosity=Heterozygous (PubMed=27600491).
  • Mutation; HGNC; HGNC:10736; SEMA5A; Simple; p.Lys378Arg; Zygosity=Homozygous (PubMed=27600491).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg273His (c.818G>A); ClinVar=VCV000012366; Zygosity=Homozygous (PubMed=27600491).
Disease Esophageal adenocarcinoma (NCIt: C4025)
Adenocarcinoma of the esophagus (ORDO: Orphanet_99976)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 55Y
Category Cancer cell line
Publications

PubMed=27600491; DOI=10.1038/srep32417; PMCID=PMC5013399
Edwin Garcia, Annette Hayden, Charles Birts, Edward Britton, Andrew Cowie, Karen Pickard, Massimiliano Mellone, Clarisa Thian Puay Choh, Mathieu F. Derouet, Patrick Duriez, Fergus Noble ...Show all 20 authors... , Michael J. White, John Neil Primrose, Jonathan C. Strefford, Matthew J. Rose-Zerilli, Gareth J. Thomas, Yeng S. Ang, Andrew D. Sharrocks, Rebecca Clare Fitzgerald, Timothy J. Underwood; Show fewer authors
OCCAMS Consortium
Authentication and characterisation of a new oesophageal adenocarcinoma cell line: MFD-1.
Sci. Rep. 6:32417-32417(2016)

Cross-references
Cell line databases/resources cancercelllines; CVCL_JY36
Encyclopedic resources Wikidata; Q54905377
Entry history
Entry creation22-Aug-2017
Last entry update10-Apr-2025
Version number15