Cellosaurus cell line 8587 (CVCL

Cellosaurus 8587 (CVCL_JY33)

[Text version]

Cell line name

8587

Accession

CVCL_JY33

Resource Identification Initiative

To cite this cell line use: 8587 (RRID:CVCL_JY33)

Comments

Doubling time: 6-9 days (PubMed=25862976).
Omics: Genomics; Whole genome sequencing; Low read coverage.
Omics: Transcriptomics; RNAseq.
Miscellaneous: Age at sampling from personal communication of Castillo-Tong, Dan Cacsire.
Derived from site: In situ; Ovary; UBERON=UBERON_0000992.

Sequence variations

Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg273His (c.818G>A); ClinVar=VCV000012366; Zygosity=Unspecified (PubMed=25862976; PubMed=31150822).

Disease

High grade ovarian serous adenocarcinoma (NCIt: C105555)

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Sex of cell

Female

Age at sampling

49Y

Category

Cancer cell line

STR profile

Source(s): PubMed=31150822

Markers:

Amelogenin	X
CSF1PO	10,13
D1S1656	16,16.3
D2S1338	20,26
D3S1358	15,17
D5S818	11,12
D6S1043	18,19
D7S820	8,12
D8S1179	14
D12S391	20,22
D13S317	11,13
D16S539	10,14
D18S51	15,17
D19S433	13
D21S11	28,30
FGA	22
Penta D	11,13
Penta E	7
TH01	9.3
TPOX	8
vWA	14

Publications

PubMed=25862976; DOI=10.1016/j.canlet.2015.03.040
Kreuzinger C., Gamperl M., Wolf A., Heinze G., Geroldinger A., Lambrechts D., Boeckx B., Smeets D., Horvat R., Aust S., Hamilton G., Zeillinger R., Castillo-Tong D.C.
Molecular characterization of 7 new established cell lines from high grade serous ovarian cancer.
Cancer Lett. 362:218-228(2015)

PubMed=31150822; DOI=10.1016/j.canlet.2019.05.032
Kreuzinger C., von der Decken I., Wolf A., Gamperl M., Koller J., Karacs J., Pfaffinger S., Bartl T., Reinthaller A., Grimm C., Singer C.F., Braicu E.I., Cunnea P., Gourley C., Smeets D., Boeckx B., Lambrechts D., Perco P., Horvat R., Berns E.M.J.J., Castillo-Tong D.C.
Patient-derived cell line models revealed therapeutic targets and molecular mechanisms underlying disease progression of high grade serous ovarian cancer.
Cancer Lett. 459:1-12(2019)

Cross-references

Cell line databases/resources

cancercelllines; CVCL_JY33

Encyclopedic resources

Wikidata; Q54605344

Entry history

Entry creation

22-Aug-2017

Last entry update

10-Apr-2025

Version number