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Cellosaurus 13914_1 (CVCL_JY30)

[Text version]
Cell line name 13914_1
Synonyms 13914
Accession CVCL_JY30
Resource Identification Initiative To cite this cell line use: 13914_1 (RRID:CVCL_JY30)
Comments Doubling time: 6-9 days (PubMed=25862976).
Omics: Genome sequenced (low read coverage).
Omics: Transcriptome analysis by RNAseq.
Miscellaneous: Age at sampling and TP53 mutation cDNA coordinates from personal communication of Cacsire Castillo-Tong D.
Derived from site: Metastatic; Ascites; UBERON=UBERON_0007795.
Sequence variations
  • Mutation; HGNC; 1100; BRCA1; Simple; p.Glu1161Phefs*3 (c.3481_3491delGAAGATACTAG); ClinVar=VCV000017684; Zygosity=Homozygous (PubMed=25862976; PubMed=31150822).
  • Mutation; HGNC; 11998; TP53; Simple; p.Met340Serfs*2 (c.1019_1028del10); Zygosity=Unspecified (PubMed=25862976; PubMed=31150822).
Disease High grade ovarian serous adenocarcinoma (NCIt: C105555)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 66Y
Category Cancer cell line
STR profile Source(s): PubMed=31150822

Markers:
AmelogeninX
CSF1PO10,12
D1S165614,17.3
D2S133819,25
D3S135815,17
D5S81812
D6S104311,19
D7S82010,11
D8S117912,13
D12S39120
D13S3178
D16S53912
D18S5113
D19S43314,14.2
D21S1130
FGA22
Penta D12
Penta E12
TH017,9.3
TPOX8,11
vWA17,18

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Publications

PubMed=25862976; DOI=10.1016/j.canlet.2015.03.040
Kreuzinger C., Gamperl M., Wolf A., Heinze G., Geroldinger A., Lambrechts D., Boeckx B., Smeets D., Horvat R., Aust S., Hamilton G., Zeillinger R., Castillo-Tong D.C.
Molecular characterization of 7 new established cell lines from high grade serous ovarian cancer.
Cancer Lett. 362:218-228(2015)

PubMed=31150822; DOI=10.1016/j.canlet.2019.05.032
Kreuzinger C., von der Decken I., Wolf A., Gamperl M., Koller J., Karacs J., Pfaffinger S., Bartl T., Reinthaller A., Grimm C., Singer C.F., Braicu E.I., Cunnea P., Gourley C., Smeets D., Boeckx B., Lambrechts D., Perco P., Horvat R., Berns E.M.J.J., Castillo-Tong D.C.
Patient-derived cell line models revealed therapeutic targets and molecular mechanisms underlying disease progression of high grade serous ovarian cancer.
Cancer Lett. 459:1-12(2019)

Cross-references
Cell line databases/resources cancercelllines; CVCL_JY30
Encyclopedic resources Wikidata; Q54581762
Entry history
Entry creation22-Aug-2017
Last entry update05-Oct-2023
Version number9