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Cellosaurus POT1a F/F (CVCL_JM06)

[Text version]
Cell line name POT1a F/F
Accession CVCL_JM06
Resource Identification Initiative To cite this cell line use: POT1a F/F (RRID:CVCL_JM06)
Comments Characteristics: Embryonic fibroblasts that have loxP sites on both sides of the 3rd coding exon of mouse Pot1a gene. Pot1a knockout can be effected by transduction of Cre recombinase into the cell line (ATCC=CRL-3321).
Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Genetic integration: Method=Transduction; Gene=UniProtKB; P03070; Simian virus 40 (SV40) large T antigen.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
Derived from site: In situ; Embryo; UBERON=UBERON_0000922.
Cell type: Fibroblast; CL=CL_0000057.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: C57BL/6J.
Sex of cell Sex unspecified
Age at sampling 13-14FD
Category Transformed cell line
Publications

PubMed=16839877; DOI=10.1016/j.cell.2006.04.044
Dirk Hockemeyer, Jan-Peter Daniels, Hiroyuki Takai, Titia de Lange;
Recent expansion of the telomeric complex in rodents: two distinct POT1 proteins protect mouse telomeres.
Cell 126:63-77(2006)

Cross-references
Cell line collections (Providers) ATCC; CRL-3321
Encyclopedic resources Wikidata; Q54947760
Entry history
Entry creation15-May-2017
Last entry update14-Aug-2025
Version number10