• Gene deletion; HGNC; 1787; CDKN2A; Zygosity=Homozygous (PubMed=31541927).
  
• Mutation; HGNC; 11998; TP53; Simple; p.His193Leu (c.578A>T); ClinVar=VCV000185822; Zygosity=Unspecified (PubMed=23613873; PubMed=31541927).
  

PubMed=8824719; DOI=10.1002/(SICI)1098-2264(199601)15:1<1::AID-GCC1>3.0.CO;2-8
Hermsen M.A.J.A., Joenje H., Arwert F., Welters M.J.P., Braakhuis B.J.M., Bagnay M., Westerveld A., Slater R.M.
Centromeric breakage as a major cause of cytogenetic abnormalities in oral squamous cell carcinoma.
Genes Chromosomes Cancer 15:1-9(1996)

PubMed=9139877; DOI=10.1002/(SICI)1097-0215(19970502)71:3<410::AID-IJC18>3.0.CO;2-J
Welters M.J.P., Fichtinger-Schepman A.M.J., Baan R.A., Hermsen M.A.J.A., van der Vijgh W.J.F., Cloos J., Braakhuis B.J.M.
Relationship between the parameters cellular differentiation, doubling time and platinum accumulation and cisplatin sensitivity in a panel of head and neck cancer cell lines.
Int. J. Cancer 71:410-415(1997)

PubMed=23613873; DOI=10.1371/journal.pone.0061555; PMCID=PMC3629194
Martens-de Kemp S.R., Dalm S.U., Wijnolts F.M.J., Brink A., Honeywell R.J., Peters G.J., Braakhuis B.J.M., Brakenhoff R.H.
DNA-bound platinum is the major determinant of cisplatin sensitivity in head and neck squamous carcinoma cells.
PLoS ONE 8:E61555-E61555(2013)

PubMed=31541927; DOI=10.1016/j.oraloncology.2019.09.004; PMCID=PMC7372097
van Harten A.M., Poell J.B., Buijze M., Brink A., Wells S.I., Leemans C.R., Wolthuis R.M.F., Brakenhoff R.H.
Characterization of a head and neck cancer-derived cell line panel confirms the distinct TP53-proficient copy number-silent subclass.
Oral Oncol. 98:53-61(2019)