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Cellosaurus VU-SCC-096 (CVCL_JL63)

[Text version]
Cell line name VU-SCC-096
Synonyms 93VU096Ta; 93VU096aT
Accession CVCL_JL63
Resource Identification Initiative To cite this cell line use: VU-SCC-096 (RRID:CVCL_JL63)
Comments Doubling time: 41 +- 3 hours (PubMed=9139877).
Omics: Genomics; Whole genome sequencing; Low read coverage.
Derived from site: In situ; Oral cavity, retromolar trigone; UBERON=UBERON_0012376.
Sequence variations
Disease Retromolar trigone squamous cell carcinoma (NCIt: C8172)
Squamous cell carcinoma of the oral cavity (ORDO: Orphanet_502363)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 42Y
Category Cancer cell line
Publications

PubMed=8824719; DOI=10.1002/(SICI)1098-2264(199601)15:1<1::AID-GCC1>3.0.CO;2-8
Mario A.J.A. Hermsen, Hans Joenje, Fre Arwert, Marij J.P. Welters, Boudewijn J.M. Braakhuis, Marian Bagnay, Andries Westerveld, Rosalyn M. Slater;
Centromeric breakage as a major cause of cytogenetic abnormalities in oral squamous cell carcinoma.
Genes Chromosomes Cancer 15:1-9(1996)

PubMed=9139877; DOI=10.1002/(SICI)1097-0215(19970502)71:3<410::AID-IJC18>3.0.CO;2-J
Marij J.P. Welters, Anne Marie Josephine Fichtinger-Schepman, Robert A. Baan, Mario A.J.A. Hermsen, Wim J.F. van der Vijgh, Jacqueline Cloos, Boudewijn J.M. Braakhuis;
Relationship between the parameters cellular differentiation, doubling time and platinum accumulation and cisplatin sensitivity in a panel of head and neck cancer cell lines.
Int. J. Cancer 71:410-415(1997)

PubMed=23613873; DOI=10.1371/journal.pone.0061555; PMCID=PMC3629194
Sanne R. Martens-de Kemp, Simone U. Dalm, Fiona M.J. Wijnolts, Arjen Brink, Richard J. Honeywell, Godefridus Johannes Peters, Boudewijn J.M. Braakhuis, Ruud H. Brakenhoff;
DNA-bound platinum is the major determinant of cisplatin sensitivity in head and neck squamous carcinoma cells.
PLoS ONE 8:e61555.1-e61555.9(2013)

PubMed=31541927; DOI=10.1016/j.oraloncology.2019.09.004; PMCID=PMC7372097
Anne M. van Harten, Jos B. Poell, Marijke Buijze, Arjen Brink, Susanne I. Wells, C. Rene Leemans, Rob M.F. Wolthuis, Ruud H. Brakenhoff;
Characterization of a head and neck cancer-derived cell line panel confirms the distinct TP53-proficient copy number-silent subclass.
Oral Oncol. 98:53-61(2019)

Cross-references
Cell line databases/resources cancercelllines; CVCL_JL63
Encyclopedic resources Wikidata; Q54993381
Entry history
Entry creation15-May-2017
Last entry update10-Apr-2025
Version number13