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Cellosaurus KH-AML-B2 (CVCL_JK50)

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Cell line name KH-AML-B2
Accession CVCL_JK50
Resource Identification Initiative To cite this cell line use: KH-AML-B2 (RRID:CVCL_JK50)
Comments Population: Japanese.
Characteristics: CSF2 dependent.
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Sequence variations
  • Mutation; HGNC; HGNC:1101; BRCA2; Simple; p.Lys2729Asn (c.8187G>T) (8415G>T); ClinVar=VCV000038142; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:1101; BRCA2; Simple; p.Ser2835Glu (c.8503_8504TC>GA) (8731TC>GA); Zygosity=Heterozygous; Note=Reverted. This cell line contains both the mutated allele and the reverted allele (from parent cell line).
  • Mutation; HGNC; HGNC:1101; BRCA2; Simple; p.Ser2835Ter (c.8504C>G) (8732C>A); ClinVar=VCV000267091; Zygosity=Heterozygous; Note=Mutated. This cell line contains both the mutated allele and the reverted allele (from parent cell line).
Disease Childhood acute myeloid leukemia (NCIt: C9160)
Fanconi anemia (NCIt: C62505)
Acute myeloid leukemia (ORDO: Orphanet_519)
Fanconi anemia (ORDO: Orphanet_84)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_JH26 (FA-AML1A)
Sex of cell Male
Age at sampling 4Y
Category Cancer cell line
Cross-references
Cell line collections (Providers) JCRB; KURB2759
Cell line databases/resources cancercelllines; CVCL_JK50
Encyclopedic resources Wikidata; Q54899858
Entry history
Entry creation15-May-2017
Last entry update10-Apr-2025
Version number11