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Cellosaurus YUMM2.2R (CVCL_JK33)

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Cell line name YUMM2.2R
Synonyms Yale University Mouse Melanoma 2.2R
Accession CVCL_JK33
Resource Identification Initiative To cite this cell line use: YUMM2.2R (RRID:CVCL_JK33)
Comments Characteristics: Has full Bcat STA/wt recombination.
Knockout cell: Method=KO mouse; MGI; MGI:104738; Cdkn2a (Note=1 of 2 alleles).
Knockout cell: Method=KO mouse; MGI; MGI:109583; Pten.
Sequence variations
  • Mutation; MGI; MGI:88190; Braf; Simple; p.Val637Glu (c.1910T>A); Zygosity=Heterozygous (PubMed=27287723).
Disease Mouse melanoma (NCIt: C21790)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: C57BL/6.
Sex of cell Male
Age at sampling Age unspecified
Category Cancer cell line
Publications

PubMed=27287723; DOI=10.1111/pcmr.12498; PMCID=PMC5331933
Katrina Meeth, Jake Xiao Wang, Goran Micevic, William Damsky, Marcus W. Bosenberg;
The YUMM lines: a series of congenic mouse melanoma cell lines with defined genetic alterations.
Pigment Cell Melanoma Res. 29:590-597(2016)

Cross-references
Encyclopedic resources Wikidata; Q54995732
Entry history
Entry creation15-May-2017
Last entry update14-Aug-2025
Version number6