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Cellosaurus ATL-12A (CVCL_JF72)

[Text version]
Cell line name ATL-12A
Synonyms ATL-12A(+); ATL-12; ATL12A; ATL12
Accession CVCL_JF72
Resource Identification Initiative To cite this cell line use: ATL-12A (RRID:CVCL_JF72)
Comments Population: Japanese.
Characteristics: IL2 dependent.
Transformant: NCBI_TaxID; 11908; Human T-lymphotropic virus 1 (HTLV-1).
Donor information: Established from a patient suffering from adult T-cell leukemia/lymphoma (ATLL).
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Cell type: T-cell; CL=CL_0000084.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Sex unspecified
Age at sampling Adult
Category Transformed cell line
Publications

PubMed=2866223; DOI=10.1084/jem.162.6.2169; PMCID=PMC2187984
Maeda M., Shimizu A., Ikuta K., Okamoto H., Kashihara M., Uchiyama T., Honjo T., Yodoi J.
Origin of human T-lymphotrophic virus I-positive T cell lines in adult T cell leukemia. Analysis of T cell receptor gene rearrangement.
J. Exp. Med. 162:2169-2174(1985)

PubMed=32210945; DOI=10.3389/fmicb.2020.00356; PMCID=PMC7067701
Maeda M., Tanabe-Shibuya J., Miyazato P., Masutani H., Yasunaga J.-i., Usami K., Shimizu A., Matsuoka M.
IL-2/IL-2 receptor pathway plays a crucial role in the growth and malignant transformation of HTLV-1-infected T cells to develop adult T-cell leukemia.
Front. Microbiol. 11:356.1-356.17(2020)

Cross-references
Cell line collections (Providers) RCB; RCB3562
Encyclopedic resources Wikidata; Q54751246
Entry history
Entry creation15-May-2017
Last entry update29-Jun-2023
Version number9