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Cellosaurus 260F9 (CVCL_J908)

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Cell line name 260F9
Accession CVCL_J908
Resource Identification Initiative To cite this cell line use: 260F9 (RRID:CVCL_J908)
Comments Group: Patented cell line.
Registration: International Depositary Authority, American Type Culture Collection (ATCC); HB-8488.
Biotechnology: The monoclonal antibody produced by this hybridoma was conjugated to a ricin chain A to produce 260F9-rRTA which was evaluated in two phase 1 clinical trials which were not pursued due to severe toxicity of the conjugate (DOI=10.3390/antib1010039).
Monoclonal antibody isotype: IgG1.
Monoclonal antibody target: Human breast/ovarian cancer 55 kDa antigen.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Hierarchy Parent: CVCL_2199 (Sp2/0-Ag14)
Children:
CVCL_J909 (260F9-1C9)
Category Hybridoma
Publications

Patent=US4753894
Arthur Edward Frankel, David Barratt Ring, Michael Jon Bjorn;
Monoclonal anti-human breast cancer antibodies.
Patent number US4753894, 28-Jun-1988

Patent=US4938948
David Barratt Ring, Arthur Edward Frankel;
Method for imaging breast tumors using labeled monoclonal anti-human breast cancer antibodies.
Patent number US4938948, 03-Jul-1990

Patent=US4956453
Michael Jon Bjorn, Arthur Edward Frankel, Walter Joseph Laird, David Barratt Ring, Jeffrey Lee Winkelhake;
Anti-human ovarian cancer immunotoxins and methods of use thereof.
Patent number US4956453, 11-Sep-1990

Patent=US5629197
David Barratt Ring, Arthur Edward Frankel, Michael Jon Bjorn;
Monoclonal anti-human breast cancer antibodies.
Patent number US5629197, 13-May-1997

DOI=10.3390/antib1010039
Nurit Becker, Itai Benhar;
Antibody-based immunotoxins for the treatment of cancer.
Antibodies (Basel) 1:39-69(2012)

Cross-references
Cell line collections (Providers) ATCC; HB-8488
Encyclopedic resources Wikidata; Q54583674
Entry history
Entry creation11-Feb-2013
Last entry update21-Mar-2023
Version number8