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Cellosaurus NCI-H460-Luc (CVCL_J264)

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Cell line name NCI-H460-Luc
Accession CVCL_J264
Resource Identification Initiative To cite this cell line use: NCI-H460-Luc (RRID:CVCL_J264)
Comments Population: Caucasian.
Genetic integration: Method=Transduction; Gene=UniProtKB; P08659; Photinus pyralis firefly-type luciferase.
Genetic integration: Method=Transduction; Gene=UniProtKB; P13249; Streptomyces alboniger pac (PuroR).
Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations
  • Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gln61His (c.183A>T); ClinVar=VCV000045117; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.Glu545Lys (c.1633G>A); ClinVar=VCV000013655; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11389; STK11; Simple; p.Gln37Ter (c.109C>T); ClinVar=VCV000376334; Zygosity=Homozygous (from parent cell line).
Disease Lung large cell carcinoma (NCIt: C4450)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0459 (NCI-H460)
Sex of cell Male
Age at sampling Age unspecified
Category Cancer cell line
STR profile Source(s): JCRB=JCRB1407

Markers:
AmelogeninX,Y
CSF1PO11,12
D5S8189,10
D7S8209,12
D13S31713
D16S5399
TH019.3
TPOX8
vWA17,18

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Cross-references
Cell line collections (Providers) JCRB; JCRB1407
JCRB; NIHS0658 - Discontinued
Cell line databases/resources cancercelllines; CVCL_J264
Encyclopedic resources Wikidata; Q54908060
Entry history
Entry creation11-Feb-2013
Last entry update14-Aug-2025
Version number21