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Cellosaurus MeWo-Luc (CVCL_J260)

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Cell line name MeWo-Luc
Synonyms Mewo-Luc
Accession CVCL_J260
Resource Identification Initiative To cite this cell line use: MeWo-Luc (RRID:CVCL_J260)
Comments Population: Caucasian.
Genetic integration: Method=Transduction; Gene=UniProtKB; P08659; Photinus pyralis firefly-type luciferase.
Genetic integration: Method=Transduction; Gene=UniProtKB; P13249; Streptomyces alboniger pac (PuroR).
Derived from site: Metastatic; Lymph node; UBERON=UBERON_0000029.
Sequence variations
  • Gene deletion; HGNC; HGNC:1788; CDKN2B; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:1787; CDKN2A; Simple; p.Arg80Ter (c.237_238CC>TT) (c.237_238delinsTT) (p.Pro94Leu, c.280_281CC>TT); Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:6877; MAPK3; Simple; p.Pro246Ser (c.736C>T); Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Gln317Ter (c.949C>T); ClinVar=VCV000450344; Zygosity=Unspecified (from parent cell line).
Disease Cutaneous melanoma (NCIt: C3510)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0445 (MeWo)
Sex of cell Male
Age at sampling 78Y
Category Cancer cell line
STR profile Source(s): JCRB=JCRB1396

Markers:
AmelogeninX,Y
CSF1PO12
D5S81812,13
D7S82010,12
D13S3178,9
D16S53910,12
TH017,9
TPOX8,10
vWA15

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Cross-references
Cell line collections (Providers) JCRB; JCRB1396
JCRB; NIHS0643 - Discontinued
Cell line databases/resources cancercelllines; CVCL_J260
Encyclopedic resources Wikidata; Q54905348
Entry history
Entry creation11-Feb-2013
Last entry update14-Aug-2025
Version number21