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Cellosaurus Oli-neu (CVCL_IZ82)

[Text version]
Cell line name Oli-neu
Synonyms Olineu; OliNeu; OLIneu
Accession CVCL_IZ82
Resource Identification Initiative To cite this cell line use: Oli-neu (RRID:CVCL_IZ82)
Comments Characteristics: Can be induced to differentiate after application of dibutyryl cAMP.
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Transformant: Activated EGFR-neu.
Omics: Transcriptomics; Microarray.
Derived from site: In situ; Embryonic brain; UBERON=UBERON_0006238.
Cell type: Oligodendrocyte; CL=CL_0000128.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: NMRI.
Hierarchy Children:
CVCL_VL76 (Oli-neuM)
Sex of cell Sex unspecified
Age at sampling 15FD
Category Transformed cell line
STR profile Source(s): Millipore=SCC261

Markers:
Mouse STR 1-114,15
Mouse STR 1-214
Mouse STR 3-210,13
Mouse STR 4-219.3
Mouse STR 5-512
Mouse STR 6-416,17,18
Mouse STR 6-711,12
Mouse STR 7-125.2,29
Mouse STR 8-116
Mouse STR 11-215
Mouse STR 12-119,20
Mouse STR 13-115
Mouse STR 15-320.3
Mouse STR 17-215,16
Mouse STR 18-317
Mouse STR 19-211,13
Mouse STR X-125

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Publications

PubMed=7582098; DOI=10.1111/j.1460-9568.1995.tb01115.x
Marion Jung, Eva-Maria Kramer-Albers, Martina Grzenkowski, Ke Tang, William F. Blakemore, Adriano Aguzzi, Khashayarsha Khazaie, Katerina Chlichlia, Gabriela von Blankenfeld, Helmut Kettenmann, Jacqueline Trotter;
Lines of murine oligodendroglial precursor cells immortalized by an activated neu tyrosine kinase show distinct degrees of interaction with axons in vitro and in vivo.
Eur. J. Neurosci. 7:1245-1265(1995)

PubMed=18439243; DOI=10.1186/1471-2202-9-40; PMCID=PMC2396630
Angelika Kippert, Katarina Trajkovic, Dirk Fitzner, Lennart Opitz, Mikael Simons;
Identification of Tmem10/Opalin as a novel marker for oligodendrocytes using gene expression profiling.
BMC Neurosci. 9:40.1-40.12(2008)

PubMed=21472765; DOI=10.1002/jnr.22625; PMCID=PMC3088771
Glauber Bruno Pereira, Anna Dobretsova, Hamdan Hamdan, Patricia A. Wight;
Expression of myelin genes: comparative analysis of Oli-neu and N20.1 oligodendroglial cell lines.
J. Neurosci. Res. 89:1070-1078(2011)

PubMed=23825458; DOI=10.3389/fphar.2013.00083; PMCID=PMC3695394
Goran Sohl, Sonja Hombach, Joachim Degen, Benjamin Odermatt;
The oligodendroglial precursor cell line Oli-neu represents a cell culture system to examine functional expression of the mouse gap junction gene connexin29 (Cx29).
Front. Pharmacol. 4:83.1-83.16(2013)

PubMed=26658258; DOI=10.1371/journal.pone.0144550; PMCID=PMC4689554
Giampiero Porcu, Eliseo Serone, Velia De Nardis, Daniele Di Giandomenico, Giuseppe Lucisano, Marco Scardapane, Anna Poma, Antonella Ragnini-Wilson;
Clobetasol and halcinonide act as Smoothened agonists to promote myelin gene expression and RxRgamma receptor activation.
PLoS ONE 10:e0144550.1-e0144550.22(2015)

Cross-references
Cell line collections (Providers) Millipore; SCC261
Encyclopedic resources Wikidata; Q54931995
Gene expression databases GEO; GSE10291
Entry history
Entry creation15-May-2017
Last entry update14-Aug-2025
Version number10