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Cellosaurus PER-703 (CVCL_IY99)

[Text version]
Cell line name PER-703
Synonyms PER-703A
Accession CVCL_IY99
Resource Identification Initiative To cite this cell line use: PER-703 (RRID:CVCL_IY99)
Comments Doubling time: 60 hours (PubMed=27443263).
Omics: Transcriptomics; RNAseq.
Miscellaneous: Sampling site from personal communication of Kotecha, Rishi S.
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Disease Infant acute lymphoblastic leukemia with MLL rearrangement (NCIt: C122617)
Acute lymphoblastic leukemia (ORDO: Orphanet_513)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_IZ00 ! PER-703S
CVCL_IZ01 ! PER-733S
Sex of cell Female
Age at sampling 1M
Category Cancer cell line
STR profile Source(s): PubMed=27443263; PubMed=33937032

Markers:
AmelogeninX
CSF1PO10,12
D5S81812
D7S82010,11
D13S31712,13
D16S5399,11
D21S1130,31.2
TH019.3
TPOX8,9
vWA17

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Publications

PubMed=27443263; DOI=10.1038/leu.2016.165; PMCID=PMC5220136
Cruickshank M.N., Ford J., Cheung L.C., Heng J., Singh S., Wells J., Failes T.W., Arndt G.M., Smithers N., Prinjha R.K., Anderson D., Carter K.W., Gout A.M., Lassmann T., O'Reilly J., Cole C.H., Kotecha R.S., Kees U.R.
Systematic chemical and molecular profiling of MLL-rearranged infant acute lymphoblastic leukemia reveals efficacy of romidepsin.
Leukemia 31:40-50(2017)

PubMed=33937032; DOI=10.3389/fonc.2021.631594; PMCID=PMC8082024
Cheung L.C., de Kraa R., Oommen J., Chua G.-A., Singh S., Hughes A.M., Ferrari E., Ford J., Chiu S.K., Stam R.W., Kees U.R., Malinge S., Kotecha R.S.
Preclinical evaluation of carfilzomib for infant KMT2A-rearranged acute lymphoblastic leukemia.
Front. Oncol. 11:631594.1-631594.13(2021)

Cross-references
Encyclopedic resources Wikidata; Q54947217
Entry history
Entry creation15-May-2017
Last entry update10-Apr-2025
Version number8