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Cellosaurus HBG BC2 (CVCL_IW93)

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Cell line name HBG BC2
Synonyms HBG-BC2; HBG, clone BC2; BC2
Accession CVCL_IW93
Resource Identification Initiative To cite this cell line use: HBG BC2 (RRID:CVCL_IW93)
Comments Characteristics: Possesses the capacity of being reversibly differentiated in vitro and of maintaining a relatively higher metabolic rate when in the differentiated state (3 weeks). May be used for repeated toxicity testing on cells in culture.
Karyotypic information: Has lost chromosome Y.
Derived from site: In situ; Liver; UBERON=UBERON_0002107.
Disease Adult hepatocellular carcinoma (NCIt: C7956)
Adult hepatocellular carcinoma (ORDO: Orphanet_210159)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_IW92 (HBG)
Sex of cell Male
Age at sampling 61Y
Category Cancer cell line
Publications

PubMed=9486853
Denise Glaise, Gennady P. Ilyin, Pascal Loyer, Sandrine Cariou, Marc Bilodeau, Josiane Lucas, Alain Puisieux, Mehmet Ozturk, Christiane Guguen-Guillouzo;
Cell cycle gene regulation in reversibly differentiated new human hepatoma cell lines.
Cell Growth Differ. 9:165-176(1998)

PubMed=12776925; DOI=10.1023/A:1023304005217
Nicolas Fabre, Elsa Arrivet, Jacques Trancard, Nicole Bichet, Nigel Oliver Roome, Annick Prenez, Joan-Albert Vericat;
A new hepatoma cell line for toxicity testing at repeated doses.
Cell Biol. Toxicol. 19:71-82(2003)

PubMed=23577442
Nicolas Fabre, Elsa Arrivet, Francoise Paillard, Valerie Wibaut-Berlaimont, Nicole Bichet, Nigel Oliver Roome, Annick Prenez, Joan-Albert Vericat;
A new human hepatoma cell line to study repeated cell toxicity.
Altern. Lab. Anim. 32 Suppl. 1A:113-116(2004)

Cross-references
Encyclopedic resources Wikidata; Q30133230
Entry history
Entry creation15-May-2017
Last entry update29-Jun-2023
Version number6