• Mutation; HGNC; HGNC:4851; HTT; Repeat_expansion; p.Gln18[33] (c.52CAG(33)) (c.52CAG[(27_35)]); ClinVar=VCV000031915; Zygosity=Heterozygous (from parent cell line).
  

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HD iPSC-derived neural progenitors accumulate in culture and are susceptible to BDNF withdrawal due to glutamate toxicity.
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Low-dose irradiation enhances gene targeting in human pluripotent stem cells.
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NeuroLINCS Consortium
NYGC ALS Consortium
An integrated multi-omic analysis of iPSC-derived motor neurons from C9ORF72 ALS patients.
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Standardization of cell culture conditions and routine genomic screening under a quality management system leads to reduced genomic instability in hPSCs.
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