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Cellosaurus USPC-ARK-5 (CVCL_IV76)

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Cell line name USPC-ARK-5
Synonyms USPC ARK-5; USPC-ARK5
Accession CVCL_IV76
Resource Identification Initiative To cite this cell line use: USPC-ARK-5 (RRID:CVCL_IV76)
Comments Population: African American.
Derived from site: In situ; Endometrium; UBERON=UBERON_0001295.
Disease Endometrial serous adenocarcinoma (NCIt: C27838)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 73Y
Category Cancer cell line
Publications

PubMed=19920829; DOI=10.1038/sj.bjc.6605448; PMCID=PMC2813756
Karim S. El-Sahwi, Stefania Bellone, Emiliano Cocco, Marilisa Cargnelutti, Francesca Casagrande, Marta Bellone, Maysa Abu-Khalaf, Natalia Buza, Fattaneh A. Tavassoli, Pei Hui, Dan-Arin Silasi ...Show all 16 authors... , Masoud Azodi, Peter E. Schwartz, Thomas J. Rutherford, Sergio Pecorelli, Alessandro D. Santin; Show fewer authors
In vitro activity of pertuzumab in combination with trastuzumab in uterine serous papillary adenocarcinoma.
Br. J. Cancer 102:134-143(2010)

PubMed=21246534; DOI=10.1002/cncr.25891; PMCID=PMC3128671
Joyce Varughese, Emiliano Cocco, Stefania Bellone, Maria de Leon, Marta Bellone, Paola Todeschini, Peter E. Schwartz, Thomas J. Rutherford, Sergio Pecorelli, Alessandro D. Santin;
Uterine serous papillary carcinomas overexpress human trophoblast-cell-surface marker (Trop-2) and are highly sensitive to immunotherapy with hRS7, a humanized anti-Trop-2 monoclonal antibody.
Cancer 117:3163-3172(2011)

PubMed=23891627; DOI=10.1016/j.ajog.2013.07.020
Diana P. English, Stefania Bellone, Emiliano Cocco, Ileana Bortolomai, Sergio Pecorelli, Salvatore Lopez, Dan-Arin Silasi, Peter E. Schwartz, Thomas J. Rutherford, Alessandro D. Santin;
Oncogenic PIK3CA gene mutations and HER2/neu gene amplifications determine the sensitivity of uterine serous carcinoma cell lines to GDC-0980, a selective inhibitor of Class I PI3 kinase and mTOR kinase (TORC1/2).
Am. J. Obstet. Gynecol. 209:465.e1-465.e9(2013)

Cross-references
Encyclopedic resources Wikidata; Q54991976
Entry history
Entry creation03-Mar-2017
Last entry update29-Jun-2023
Version number5