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Cellosaurus OCUM-2M/SN38 (CVCL_IV71)

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Cell line name OCUM-2M/SN38
Accession CVCL_IV71
Resource Identification Initiative To cite this cell line use: OCUM-2M/SN38 (RRID:CVCL_IV71)
Comments Population: Japanese.
Selected for resistance to: ChEBI; CHEBI_8988; SN-38 (7-ethyl-10-hydroxy-camptothecin).
Derived from site: In situ; Stomach; UBERON=UBERON_0000945.
Disease Gastric diffuse adenocarcinoma (NCIt: C9159)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_8383 (OCUM-2M)
Sex of cell Female
Age at sampling 49Y
Category Cancer cell line
Publications

PubMed=20393015
Xiao-Tian Zhang, Masakazu Yashiro, Hong Qiu, Takafumi Nishii, Taro Matsuzaki, Kosei Hirakawa;
Establishment and characterization of multidrug-resistant gastric cancer cell lines.
Anticancer Res. 30:915-921(2010)

PubMed=21997136; DOI=10.1038/bjc.2011.397; PMCID=PMC3242520
Masakazu Yashiro, Hong Qiu, Tsuyoshi Hasegawa, Xiao-Tian Zhang, Taro Matsuzaki, Kosei Hirakawa;
An EGFR inhibitor enhances the efficacy of SN38, an active metabolite of irinotecan, in SN38-refractory gastric carcinoma cells.
Br. J. Cancer 105:1522-1532(2011)

Cross-references
Encyclopedic resources Wikidata; Q54931831
Entry history
Entry creation03-Mar-2017
Last entry update19-Dec-2024
Version number8