| Cell line name |
DH978 |
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| Accession |
CVCL_IV32 |
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| Resource Identification Initiative |
To cite this cell line use: DH978 (RRID:CVCL_IV32) |
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| Comments |
Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
Cell type: B-cell; CL=CL_0000236. |
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| Sequence variations |
- Mutation; HGNC; HGNC:1784; CDKN1A; Simple; p.Phe63Leu (c.189C>A); Zygosity=Heterozygous (PubMed=7882347).
- Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg248Gln (c.743G>A); ClinVar=VCV000012356; Zygosity=Heterozygous (PubMed=7757991).
|
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| Disease |
EBV-related Burkitt lymphoma (NCIt: C27694)
Burkitt lymphoma (ORDO: Orphanet_543) |
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| Species of origin |
Homo sapiens (Human)
(NCBI Taxonomy: 9606) |
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| Sex of cell |
Sex unspecified |
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| Age at sampling |
Age unspecified |
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| Category |
Cancer cell line |
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| Publications | PubMed=8515068; DOI=10.4049/jimmunol.150.12.5418
Jain V.K., Judde J.-G., Max E.E., Magrath I.T.
Variable IgH chain enhancer activity in Burkitt's lymphomas suggests an additional, direct mechanism of c-myc deregulation.
J. Immunol. 150:5418-5428(1993) PubMed=7757991
Bae I., Fan S.-J., Bhatia K.G., Kohn K.W., Fornace A.J. Jr., O'Connor P.M.
Relationships between G1 arrest and stability of the p53 and p21Cip1/Waf1 proteins following gamma-irradiation of human lymphoma cells.
Cancer Res. 55:2387-2393(1995) PubMed=7882347
Bhatia K.G., Fan S.-J., Spangler G., Weintraub M., O'Connor P.M., Judde J.-G., Magrath I.T.
A mutant p21 cyclin-dependent kinase inhibitor isolated from a Burkitt's lymphoma.
Cancer Res. 55:1431-1435(1995) |
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| Cross-references |
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| Encyclopedic resources |
Wikidata; Q54831067
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| Entry history |
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| Entry creation | 03-Mar-2017 |
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| Last entry update | 10-Apr-2025 |
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| Version number | 10 |
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