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Cellosaurus MCF 10A-H2B-mCherry (CVCL_IV14)

[Text version]
Cell line name MCF 10A-H2B-mCherry
Accession CVCL_IV14
Resource Identification Initiative To cite this cell line use: MCF 10A-H2B-mCherry (RRID:CVCL_IV14)
Comments Characteristics: Retroviral transformation with an H2B-mCherry expression cassette.
Genetic integration: Method=Transfection/transduction; Gene=FPbase; ZERB6; mCherry (Note=Red fluorescent protein derived from drFP583 (dsRed)).
Derived from site: In situ; Breast, epithelium; UBERON=UBERON_0008367.
Sequence variations
  • Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
  • Gene deletion; HGNC; HGNC:1788; CDKN2B; Zygosity=Homozygous (from parent cell line).
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0598 (MCF-10A)
Sex of cell Female
Age at sampling 36Y
Category Spontaneously immortalized cell line
Publications

PubMed=27135972; DOI=10.1038/nmeth.3853; PMCID=PMC4887336
Marc Hafner, Mario Niepel, Mirra Chung, Peter Karl Sorger;
Growth rate inhibition metrics correct for confounders in measuring sensitivity to cancer drugs.
Nat. Methods 13:521-527(2016)

Cross-references
Cell line databases/resources LINCS_HMS; 51124
Encyclopedic resources Wikidata; Q54904277
Entry history
Entry creation03-Mar-2017
Last entry update19-Dec-2024
Version number13