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Cellosaurus PSU-SK-1 (CVCL_IU86)

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Cell line name PSU-SK-1
Accession CVCL_IU86
Resource Identification Initiative To cite this cell line use: PSU-SK-1 (RRID:CVCL_IU86)
Comments Senescence: Senesces at 35 PDL (PubMed=27698927).
Doubling time: 24 hours (Note=At 7th passage), 72 hours (Note=At 30th passage) (PubMed=27698927).
Derived from site: In situ; Kidney; UBERON=UBERON_0002113.
Sequence variations
  • Mutation; HGNC; HGNC:2514; CTNNB1; Simple; p.Ser45Pro (c.133T>C); ClinVar=VCV000017589; Zygosity=Unspecified (PubMed=27698927).
  • Mutation; HGNC; HGNC:12796; WT1; Simple; p.Arg433Ter (c.1297C>T) (R413*) (R430*); Zygosity=Unspecified (PubMed=27698927).
Disease Kidney Wilms tumor (NCIt: C40407)
WAGR syndrome (NCIt: C3718)
Nephroblastoma (ORDO: Orphanet_654)
WAGR syndrome (ORDO: Orphanet_893)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 8Y
Category Finite cell line
Publications

PubMed=27698927; DOI=10.7150/jca.16316; PMCID=PMC5039371
Korkiat Theerakitthanakul, Jirakrit Kruatong, Jirasak Kruatong, Potchanapond Graidist, Pritsana Raungrut, Kanita Kayasut, Surasak Sangkhathat;
Senescence process in primary Wilms' tumor cell culture induced by p53 independent p21 expression.
J. Cancer 7:1867-1876(2016)

Cross-references
Encyclopedic resources Wikidata; Q54948616
Polymorphism and mutation databases Cosmic; 2569715
Entry history
Entry creation03-Mar-2017
Last entry update27-Nov-2025
Version number15