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Cellosaurus Pre-Alp (CVCL_IU85)

[Text version]
Cell line name Pre-Alp
Synonyms PRE-ALP; PreALP
Accession CVCL_IU85
Resource Identification Initiative To cite this cell line use: Pre-Alp (RRID:CVCL_IU85)
Comments Doubling time: ~24 hours (PubMed=8464241).
Derived from site: In situ; Bone marrow; UBERON=UBERON_0002371.
Sequence variations
Disease Childhood B acute lymphoblastic leukemia (NCIt: C9140)
B acute lymphoblastic leukemia with t(1;19)(q23;p13.3) E2A-PBX1 (TCF3-PBX1) (NCIt: C80347)
B-lymphoblastic leukemia/lymphoma with t(1;19)(q23;p13.3) (ORDO: Orphanet_585956)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 6Y
Category Cancer cell line
Publications

PubMed=8464241
Pandrau-Garcia D., Frances V., Martinez-Valdez H., Pages M.-P., Manel A.-M., Philippe N., Banchereau J., Saeland S.
Characterization of a t(1;19) pre-B acute lymphoblastic leukemia (ALL) cell line which proliferates in response to IL-7.
Leukemia 7:635-642(1993)

PubMed=7919343; DOI=10.1182/blood.V84.7.2253.2253
Renard N., Duvert V., Banchereau J., Saeland S.
Interleukin-13 inhibits the proliferation of normal and leukemic human B-cell precursors.
Blood 84:2253-2260(1994)

PubMed=9067587; DOI=10.1038/sj.leu.2400571
Uphoff C.C., MacLeod R.A.F., Denkmann S.A., Golub T.R., Borkhardt A., Janssen J.W.G., Drexler H.G.
Occurrence of TEL-AML1 fusion resulting from (12;21) translocation in human early B-lineage leukemia cell lines.
Leukemia 11:441-447(1997)

DOI=10.1016/B978-0-12-221970-2.50457-5
Drexler H.G.
The leukemia-lymphoma cell line factsbook.
(In book) ISBN 9780122219702; pp.1-733; Academic Press; London; United Kingdom (2001)

PubMed=29786757; DOI=10.1007/s12185-018-2474-7
Tomoyasu C., Imamura T., Tomii T., Yano M., Asai D., Goto H., Shimada A., Sanada M., Iwamoto S., Takita J., Minegishi M., Inukai T., Sugita K., Hosoi H.
Copy number abnormality of acute lymphoblastic leukemia cell lines based on their genetic subtypes.
Int. J. Hematol. 108:312-318(2018)

PubMed=35124168; DOI=10.1016/j.jsbmb.2022.106068
Tamai M., Kasai S., Akahane K., Thu T.N., Kagami K., Komatsu C., Abe M., Watanabe A., Goi K., Miyake K., Inaba T., Takita J., Goto H., Minegishi M., Iwamoto S., Sugita K., Inukai T.
Glucocorticoid receptor gene mutations confer glucocorticoid resistance in B-cell precursor acute lymphoblastic leukemia.
J. Steroid Biochem. Mol. Biol. 218:106068.1-106068.12(2022)

Cross-references
Encyclopedic resources Wikidata; Q54948341
Polymorphism and mutation databases Cosmic; 2491073
Entry history
Entry creation03-Mar-2017
Last entry update19-Dec-2024
Version number10