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Cellosaurus SK-L1 (CVCL_IU60)

[Text version]
Cell line name SK-L1
Synonyms SK-LI; SKL-1; SKL 1; SKL1
Accession CVCL_IU60
Resource Identification Initiative To cite this cell line use: SK-L1 (RRID:CVCL_IU60)
Comments From: Memorial Sloan Kettering Cancer Center; New York; USA.
Doubling time: 30 hours (PubMed=5229525).
Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Disease Adult acute myelomonocytic leukemia (NCIt: C7962)
Acute myelomonocytic leukemia (ORDO: Orphanet_517)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 51Y
Category Cancer cell line
Publications

PubMed=4169243; DOI=10.1093/jnci/39.5.1027
George Klein, Peter Clifford, Eva Klein, Richard T. Smith, Jun Minowada, Francois M. Kourilsky, Joseph Holland Burchenal;
Membrane immunofluorescence reactions of Burkitt lymphoma cells from biopsy specimens and tissue cultures.
J. Natl. Cancer Inst. 39:1027-1044(1967)

PubMed=4170382
Bayard Delafield Clarkson Sr.;
On the cellular origins and distinctive features of cultured cell lines derived from patients with leukemias and lymphomas.
Cancer Res. 27:2483-2488(1967)

PubMed=5229350; DOI=10.1093/jnci/38.5.683
Harald zur Hausen;
Chromosomal changes of similar nature in seven established cell lines derived from the peripheral blood of patients with leukemia.
J. Natl. Cancer Inst. 38:683-696(1967)

PubMed=5229525; DOI=10.1002/1097-0142(196706)20:6<926::AID-CNCR2820200603>3.0.CO;2-4
Bayard Delafield Clarkson Sr., Annabel Strife, Etienne de Harven;
Continuous culture of seven new cell lines (SK-L1 to 7) from patients with acute leukemia.
Cancer 20:926-947(1967)

PubMed=5640868
Charles P. Miles, Frank O'Neill, Donald Armstrong, Bayard Delafield Clarkson Sr., Julie Keane;
Chromosome patterns of human leukocyte established cell lines.
Cancer Res. 28:481-490(1968)

PubMed=4325933; DOI=10.1093/jnci/46.6.1243
Gary R. Pearson, Gertrude Szpingier Henle, Werner Henle;
Production of antigens associated with Epstein-Barr virus in experimentally infected lymphoblastoid cell lines.
J. Natl. Cancer Inst. 46:1243-1250(1971)

PubMed=170370; DOI=10.1099/0022-1317-28-2-207
Alice Adams, Hans Strander, Kari Cantell;
Sensitivity of the Epstein-Barr virus transformed human lymphoid cell lines to interferon.
J. Gen. Virol. 28:207-217(1975)

PubMed=7316467; DOI=10.1111/j.1469-1809.1980.tb00953.x
Susan Povey, Stephen Jeremiah, Elizabeth Arthur, Michael Steel, George Klein;
Differences in genetic stability between human cell lines from patients with and without lymphoreticular malignancy.
Ann. Hum. Genet. 44:119-133(1980)

Cross-references
Encyclopedic resources Wikidata; Q54953680
Entry history
Entry creation03-Mar-2017
Last entry update14-Aug-2025
Version number11