Cellosaurus cell line FL-518 (CVCL

Cellosaurus FL-518 (CVCL_IU41)

Cross-references
Cell line name	FL-518
Synonyms	FL518
Accession	CVCL_IU41
Resource Identification Initiative	To cite this cell line use: FL-518 (RRID:CVCL_IU41)
Comments	Population: Japanese. Omics: Transcriptomics; Microarray. Misspelling: AKA96-5; IARC_TP53=6001; Note=Not really a misspelling but an assignment of a name based on first author of publication and date because assignment of correct cell line name was not done correctly.
Sequence variations	Gene fusion; HGNC; HGNC:990; BCL2 + HGNC; HGNC:5477; IGH; Name(s)=IGH-BCL2 (PubMed=12967475). Mutation; HGNC; HGNC:11998; TP53; Simple; p.Cys176Ser (c.527G>C); Zygosity=Unspecified (PubMed=8878455).
Disease	Follicular lymphoma (NCIt: C3209) Follicular lymphoma (ORDO: Orphanet_545)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell	Male
Age at sampling	Age unspecified
Category	Cancer cell line
Publications	PubMed=8878455; DOI=10.1111/j.1349-7006.1996.tb02122.x; PMCID=PMC5921203 Takashi Akasaka, Mikiko Muramatsu, Norimitsu Kadowaki, Hitoshi Ohno, Kanji Ishizaki, Hirohiko Yamabe, Shiro Fukuhara, Minoru Okuma; p53 mutation in B-cell lymphoid neoplasms with reference to oncogene rearrangements associated with chromosomal translocations. Jpn. J. Cancer Res. 87:930-937(1996) PubMed=12967475; DOI=10.1111/j.1349-7006.2003.tb01518.x; PMCID=PMC11160262 Yoshitomo Maesako, Takashi Uchiyama, Hitoshi Ohno; Comparison of gene expression profiles of lymphoma cell lines from transformed follicular lymphoma, Burkitt's lymphoma and de novo diffuse large B-cell lymphoma. Cancer Sci. 94:774-781(2003) PubMed=14990977; DOI=10.1038/sj.leu.2403323 Mardiah Suci Hardianti, Eiji Tatsumi, Meilani Syampurnawati, Kiyoshi Furuta, Katsuyasu Saigo, Yuji Nakamachi, Shunichi Kumagai, Hitoshi Ohno, Satoru Tanabe, M. Uchida, Norimasa Yasuda; Activation-induced cytidine deaminase expression in follicular lymphoma: association between AID expression and ongoing mutation in FL. Leukemia 18:826-831(2004)
Encyclopedic resources	Wikidata; Q54834958
Polymorphism and mutation databases	IARC_TP53; 6001
Entry history
Entry creation	03-Mar-2017
Last entry update	10-Apr-2025
Version number	10