| Publications | PubMed=25939062; DOI=10.1038/nm.3855; PMCID=PMC4862411
Catherine S. Grasso, Yu-Jie Tang, Nathalene Truffaux, Noah E. Berlow, Li-Ning Liu, Marie-Anne Debily, Michael J. Quist, Lara E. Davis, Elaine C. Huang, Pamelyn J. Woo, Anitha Ponnuswami ...Show all 40 authors... , Spenser Chen, Tessa B. Johung, Wen-Chao Sun, Mari Kogiso, Yu-Chen Du, Lin Qi, Yu-Lun Huang, Marianne Hutt-Cabezas, Katherine E. Warren, Ludivine Le Dret, Paul S. Meltzer, Hua Mao, Martha Quezado, Dannis G. van Vuurden, Jinu Abraham, Maryam Fouladi, Matthew N. Svalina, Nicholas Wang, Cynthia Hawkins, Javad Nazarian, Marta M. Alonso, Eric Hutton Raabe, Esther Hulleman, Paul T. Spellman, Xiao-Nan Li, Charles Keller, Ranadip Pal, Jacques Grill, Michelle Monje; Show fewer authors
Functionally defined therapeutic targets in diffuse intrinsic pontine glioma.
Nat. Med. 21:555-559(2015) PubMed=26115193; DOI=10.1097/NEN.0000000000000216; PMCID=PMC4596247
Isabella C. Taylor, Marianne Hutt-Cabezas, William D. Brandt, Madhuri Kambhampati, Javad Nazarian, Howard T. Chang, Katherine E. Warren, Charles George Eberhart, Eric Hutton Raabe;
Disrupting NOTCH slows diffuse intrinsic pontine glioma growth, enhances radiation sensitivity, and shows combinatorial efficacy with bromodomain inhibition.
J. Neuropathol. Exp. Neurol. 74:778-790(2015) PubMed=28823557; DOI=10.1016/j.cell.2017.07.016; PMCID=PMC5587159
Elizabeth Y. Qin, Dominique D. Cooper, Keene L. Abbott, James Lennon, Surya Nagaraja, Alan Mackay, Chris Jones, Hannes Vogel, Peter K. Jackson, Michelle Monje;
Neural precursor-derived pleiotrophin mediates subventricular zone invasion by glioma.
Cell 170:845-859.e19(2017) PubMed=31439867; DOI=10.1038/s41467-019-11732-6; PMCID=PMC6706443
Nathan R. Fons, Ranjini K. Sundaram, Gregory A. Breuer, Sen Peng, Ryan L. McLean, Aravind N. Kalathil, Mark S. Schmidt, Diana M. Carvalho, Alan Mackay, Chris Jones, Angel Montero Carcaboso ...Show all 15 authors... , Javad Nazarian, Michael E. Berens, Charles Brenner, Ranjit S. Bindra; Show fewer authors
PPM1D mutations silence NAPRT gene expression and confer NAMPT inhibitor sensitivity in glioma.
Nat. Commun. 10:3790.1-3790.10(2019) PubMed=33319914; DOI=10.1093/gigascience/giaa136; PMCID=PMC7736793
Lauren M. Sanders, Allison Cheney, Lucas Seninge, Anouk van den Bout, Marissa Chen, Holly Conley Beale, Ellen Towle Kephart, Jacob Pfeil, Katrina Learned, A. Geoffrey Lyle, Isabel Bjork ...Show all 14 authors... , David Haussler, Sofie Reda Salama, Olena M. Vaske; Show fewer authors
Identification of a differentiation stall in epithelial mesenchymal transition in histone H3-mutant diffuse midline glioma.
GigaScience 9:giaa136.1-giaa136.14(2020) PubMed=34078608; DOI=10.1126/sciadv.abg4126; PMCID=PMC10166578
Juan Wang, Tina Yi-Ting Huang, Ye Hou, Elizabeth Thomas Bartom, Xin-Yan Lu, Ali Shilatifard, Feng Yue, Amanda Muhs Saratsis;
Epigenomic landscape and 3D genome structure in pediatric high-grade glioma.
Sci. Adv. 7:eabg4126.1-eabg4126.16(2021) PubMed=34215733; DOI=10.1038/s41467-021-24168-8; PMCID=PMC8253809
Chen He, Ke Xu, Xiao-Yan Zhu, Paige S. Dunphy, Brian Gudenas, Wen-Wei Lin, Nathaniel Twarog, Laura D. Hover, Chang-Hyuk Kwon, Lawryn Heath Kasper, Jun-Yuan Zhang ...Show all 40 authors... , Xiao-Yu Li, James Dalton, Barbara Jonchere, Kimberly S. Mercer, Duane G. Currier, William Caufield, Ying-Zhe Wang, Jia Xie, Alberto Broniscer, Cynthia Wetmore, Santhosh A. Upadhyaya, Ibrahim Qaddoumi, Paul Klimo, Frederick A. Boop, Amar Gajjar, Jing-Hui Zhang, Brent A. Orr, Giles W. Robinson, Michelle Monje, Burgess B. Freeman 3rd, Martine Francoise Roussel, Paul A. Northcott, Tao-Sheng Chen, Zoran Rankovic, Gang Wu, Jason Cheng-Hsuan Chiang, Christopher L. Tinkle, Anang A. Shelat, Suzanne J. Baker; Show fewer authors
Patient-derived models recapitulate heterogeneity of molecular signatures and drug response in pediatric high-grade glioma.
Nat. Commun. 12:4089.1-4089.17(2021) PubMed=34732238; DOI=10.1186/s40478-021-01270-y; PMCID=PMC8565061
Cheng Xu, Heng Liu, Christopher J. Pirozzi, Lee H. Chen, Paula K. Greer, Bill H. Diplas, Li-Wei Zhang, Matthew S. Waitkus, Yi-Ping He, Hai Yan;
TP53 wild-type/PPM1D mutant diffuse intrinsic pontine gliomas are sensitive to a MDM2 antagonist.
Acta Neuropathol. Commun. 9:178.1-178.12(2021) |
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