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Cellosaurus NEM157 (CVCL_IT35)

[Text version]
Cell line name NEM157
Accession CVCL_IT35
Resource Identification Initiative To cite this cell line use: NEM157 (RRID:CVCL_IT35)
Comments Doubling time: 30 hours (PubMed=25534822).
Derived from site: In situ; Brainstem, pons; UBERON=UBERON_0000988.
Sequence variations
Disease Diffuse intrinsic pontine glioma (NCIt: C94764)
Diffuse intrinsic pontine glioma (ORDO: Orphanet_497188)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 5Y
Category Cancer cell line
STR profile Source(s): PubMed=25939062

Markers:
AmelogeninX
CSF1PO11,12
D5S81811,12
D7S82011
D13S31711
D16S53912
D21S1130
TH019,9.3
TPOX8
vWA15,16

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Publications

PubMed=25534822; DOI=10.1093/neuonc/nou330; PMCID=PMC5654348
Nathalene Truffaux, Cathy Philippe, Janna Paulsson, Felipe Andreiuolo, Lea Guerrini-Rousseau, Gaetan Cornilleau, Ludivine Le Dret, Catherine Richon, Ludovic Lacroix, Stephanie Puget, Birgit Geoerger ...Show all 14 authors... , Gilles Vassal, Arne Ostman, Jacques Grill; Show fewer authors
Preclinical evaluation of dasatinib alone and in combination with cabozantinib for the treatment of diffuse intrinsic pontine glioma.
Neuro-oncol. 17:953-964(2015)

PubMed=25939062; DOI=10.1038/nm.3855; PMCID=PMC4862411
Catherine S. Grasso, Yu-Jie Tang, Nathalene Truffaux, Noah E. Berlow, Li-Ning Liu, Marie-Anne Debily, Michael J. Quist, Lara E. Davis, Elaine C. Huang, Pamelyn J. Woo, Anitha Ponnuswami ...Show all 40 authors... , Spenser Chen, Tessa B. Johung, Wen-Chao Sun, Mari Kogiso, Yu-Chen Du, Lin Qi, Yu-Lun Huang, Marianne Hutt-Cabezas, Katherine E. Warren, Ludivine Le Dret, Paul S. Meltzer, Hua Mao, Martha Quezado, Dannis G. van Vuurden, Jinu Abraham, Maryam Fouladi, Matthew N. Svalina, Nicholas Wang, Cynthia Hawkins, Javad Nazarian, Marta M. Alonso, Eric Hutton Raabe, Esther Hulleman, Paul T. Spellman, Xiao-Nan Li, Charles Keller, Ranadip Pal, Jacques Grill, Michelle Monje; Show fewer authors
Functionally defined therapeutic targets in diffuse intrinsic pontine glioma.
Nat. Med. 21:555-559(2015)

Cross-references
Cell line databases/resources cancercelllines; CVCL_IT35
Encyclopedic resources Wikidata; Q54930394
Entry history
Entry creation03-Mar-2017
Last entry update19-Dec-2024
Version number12