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Cellosaurus U3121MG (CVCL_IS02)

[Text version]
Cell line name U3121MG
Synonyms U3121-MG; U3121
Accession CVCL_IS02
Resource Identification Initiative To cite this cell line use: U3121MG (RRID:CVCL_IS02)
Comments Part of: Human Glioblastoma Cell Culture (HGCC) resource.
Omics: Transcriptomics; Microarray.
Omics: Variations; SNP array analysis.
Derived from site: In situ; Brain; UBERON=UBERON_0000955.
Sequence variations
  • Mutation; HGNC; HGNC:3236; EGFR; Unexplicit; Ex2-5del; Zygosity=Unspecified (PubMed=27974212).
Disease Glioblastoma (NCIt: C3058)
Glioblastoma (ORDO: Orphanet_360)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 64Y
Category Cancer cell line
STR profile Source(s): PubMed=27974212

Markers:
AmelogeninX,Y
CSF1PO9,12
D2S133816,17
D3S135814,15
D5S8187,12
D7S82010,13
D8S117913,14
D13S31712
D16S53911,12
D18S5112,14
D19S43313,15.2
D21S1128,30
FGA19,24
TH019.3
TPOX8,9
vWA17,19

Run an STR similarity search on this cell line
Web pages Provider; HGCC; -; https://www.hgcc.se/
Publications

PubMed=26629530; DOI=10.1016/j.ebiom.2015.08.026; PMCID=PMC4634360
Yuan Xie, Tobias Bergstrom, Yi-Wen Jiang, Patrik Johansson, Voichita Dana Marinescu, Nanna Lindberg, Anna Segerman, Grzegorz Wicher, Mia Niklasson, Sathishkumar Baskaran, Smitha Sreedharan ...Show all 23 authors... , Isabelle Everlien, Marianne Kastemar, Annika Hermansson, Lioudmila Elfineh, Sylwia Libard, Eric Charles Holland, Goran Hesselager, Irina Alafuzoff, Bengt Westermark, Sven Nelander, Karin Forsberg-Nilsson, Lene Uhrbom; Show fewer authors
The Human Glioblastoma Cell Culture resource: validated cell models representing all molecular subtypes.
EBioMedicine 2:1351-1363(2015)

PubMed=27974212; DOI=10.1016/j.celrep.2016.11.056
Anna Segerman, Mia Niklasson, Caroline Haglund, Tobias Bergstrom, Malin Jarvius, Yuan Xie, Ann Westermark, Demet Sonmez, Annika Hermansson, Marianne Kastemar, Zeinab Naimaie-Ali ...Show all 21 authors... , Frida Nyberg, Malin Berglund, Magnus Sundstrom, Goran Hesselager, Lene Uhrbom, Mats Gustafsson, Rolf Larsson, Marten Fryknas, Bo Segerman, Bengt Westermark; Show fewer authors
Clonal variation in drug and radiation response among glioma-initiating cells is linked to proneural-mesenchymal transition.
Cell Rep. 17:2994-3009(2016)

PubMed=28122246; DOI=10.1016/j.celrep.2017.01.003
Yi-Wen Jiang, Voichita Dana Marinescu, Yuan Xie, Malin Jarvius, Naga Prathyusha Maturi, Caroline Haglund, Sara Olofsson, Nanna Lindberg, Tommie Olofsson, Caroline Leijonmarck, Goran Hesselager ...Show all 16 authors... , Irina Alafuzoff, Marten Fryknas, Rolf Larsson, Sven Nelander, Lene Uhrbom; Show fewer authors
Glioblastoma cell malignancy and drug sensitivity are affected by the cell of origin.
Cell Rep. 18:977-990(2017)

Cross-references
Cell line databases/resources cancercelllines; CVCL_IS02
Encyclopedic resources Wikidata; Q54973733
Gene expression databases GEO; GSM1857612
GEO; GSM1857828
GEO; GSM2368454
GEO; GSM2368585
Polymorphism and mutation databases Progenetix; CVCL_IS02
Entry history
Entry creation03-Mar-2017
Last entry update10-Apr-2025
Version number10