Cellosaurus cell line HGG-02 (CVCL

Cross-references
Cell line name	HGG-02
Accession	CVCL_IR54
Resource Identification Initiative	To cite this cell line use: HGG-02 (RRID:CVCL_IR54)
Comments	Derived from site: In situ; Brain, right parieto-occipital lobe.
Sequence variations	Gene deletion; HGNC; HGNC:3236; EGFR; Zygosity=Heterozygous (PubMed=20195615). Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg273Cys (c.817C>T); ClinVar=VCV000043594; Zygosity=Unspecified (PubMed=20195615).
Disease	Glioblastoma (NCIt: C3058) Glioblastoma (ORDO: Orphanet_360)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell	Male
Age at sampling	14-15Y
Category	Cancer cell line
Publications	PubMed=20195615; DOI=10.1007/s00381-010-1110-5 Renata Veselska, Jan Skoda, Tomas Loja, Karel Zitterbart, Zdenek Pavelka, Jana Smardova, Iveta Valaskova, Marketa Hermanova, Jaroslav Sterba; An unusual loss of EGFR gene copy in glioblastoma multiforme in a child: a case report and analysis of a successfully derived HGG-02 cell line. Childs Nerv. Syst. 26:841-846(2010) PubMed=24270553; DOI=10.3892/or.2013.2864 Jan Skoda, Jakub Neradil, Karel Zitterbart, Jaroslav Sterba, Renata Veselska; EGFR signaling in the HGG-02 glioblastoma cell line with an unusual loss of EGFR gene copy. Oncol. Rep. 31:480-487(2014)
Cell line databases/resources	cancercelllines; CVCL_IR54
Encyclopedic resources	Wikidata; Q54887266
Polymorphism and mutation databases	IARC_TP53; 28524
Entry history
Entry creation	03-Mar-2017
Last entry update	19-Dec-2024
Version number	11