Cellosaurus logo
expasy logo

Cellosaurus TOV-112DR (CVCL_IQ56)

[Text][XML][JSON]
Cell line name TOV-112DR
Synonyms TOV112DR
Accession CVCL_IQ56
Resource Identification Initiative To cite this cell line use: TOV-112DR (RRID:CVCL_IQ56)
Comments Population: Caucasian.
Selected for resistance to: ChEBI; CHEBI_31355; Carboplatin (CBP; Paraplatin).
Omics: Proteomics.
Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
Sequence variations
  • Mutation; HGNC; HGNC:2514; CTNNB1; Simple; p.Ser37Ala (c.109T>G); ClinVar=VCV000376235; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11100; SMARCA4; Simple; p.Leu639fs (c.1915delC); Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg175His (c.524G>A); ClinVar=VCV000012374; Zygosity=Unspecified (from parent cell line).
Disease Ovarian endometrioid adenocarcinoma (NCIt: C7979)
Endometrioid carcinoma of ovary (ORDO: Orphanet_454723)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_3612 (TOV-112D)
Sex of cell Female
Age at sampling 42Y
Category Cancer cell line
Publications

PubMed=27561551; DOI=10.1038/ncomms12645; PMCID=PMC5007461
Fabian Coscia, Karen M. Watters, Marion Curtis, Mark A. Eckert, Chun-Yi Chiang, Stefka Tyanova, Anthony Montag, Ricardo R. Lastra, Ernst Robert Lengyel, Matthias Mann;
Integrative proteomic profiling of ovarian cancer cell lines reveals precursor cell associated proteins and functional status.
Nat. Commun. 7:12645.1-12645.14(2016)

Cross-references
Cell line databases/resources cancercelllines; CVCL_IQ56
Encyclopedic resources Wikidata; Q54972796
Proteomic databases PRIDE; PXD003668
Entry history
Entry creation03-Mar-2017
Last entry update10-Apr-2025
Version number12