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Cellosaurus HLY-1 eIF4E3 (CVCL_IN95)

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Cell line name HLY-1 eIF4E3
Accession CVCL_IN95
Resource Identification Initiative To cite this cell line use: HLY-1 eIF4E3 (RRID:CVCL_IN95)
Comments Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:31837; EIF4E3.
Omics: Transcriptomics; Microarray.
Sequence variations
  • Mutation; HGNC; HGNC:7562; MYD88; Simple; p.Ser206Cys (c.617C>G) (p.Ser219Cys, c.656C>G) (S219C); Zygosity=Heterozygous (from parent cell line).
Disease Diffuse large B-cell lymphoma activated B-cell type (NCIt: C36081)
Diffuse large B-cell lymphoma (ORDO: Orphanet_544)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_H207 (HLY-1)
Sex of cell Sex unspecified
Age at sampling Age unspecified
Category Cancer cell line
Publications

PubMed=25403230; DOI=10.1038/ncomms6413; PMCID=PMC4238046
Ari L. Landon, Parameswary A. Muniandy, Amol Carl Shetty, Elin Lehrmann, Laurent Volpon, Simone Houng, Yong-Qing Zhang, Bo-Jie Dai, Raymond Joseph Peroutka 3rd, Krystyna Mazan-Mamczarz, James Steinhardt ...Show all 15 authors... , Anup Mahurkar, Kevin G. Becker, Katherine L.B. Borden, Ronald Benjamin Gartenhaus; Show fewer authors
MNKs act as a regulatory switch for eIF4E1 and eIF4E3 driven mRNA translation in DLBCL.
Nat. Commun. 5:5413.1-5413.15(2014)

Cross-references
Encyclopedic resources Wikidata; Q54889872
Gene expression databases GEO; GSM1511352
GEO; GSM1511353
GEO; GSM1511354
GEO; GSM1511364
GEO; GSM1511365
GEO; GSM1511366
Entry history
Entry creation03-Mar-2017
Last entry update10-Apr-2025
Version number10