Cellosaurus cell line CF-KM4 (CVCL

Cross-references
Cell line name	CF-KM4
Accession	CVCL_IN80
Resource Identification Initiative	To cite this cell line use: CF-KM4 (RRID:CVCL_IN80)
Comments	Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40). Derived from site: In situ; Trachea gland; UBERON=UBERON_0005203. Cell type: Serous cell of epithelium of trachea; CL=CL_1000330.
Sequence variations	Mutation; HGNC; HGNC:1884; CFTR; Simple; p.Phe508del (c.1521_1523delCTT); ClinVar=VCV000007105; Zygosity=Homozygous (PubMed=10101000).
Disease	Cystic fibrosis (NCIt: C2975) Cystic fibrosis (ORDO: Orphanet_586)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell	Sex unspecified
Age at sampling	Adult
Category	Transformed cell line
Publications	PubMed=10101000; DOI=10.1165/ajrcmb.20.4.3341 Wafa Kammouni, Bertrand Moreau, Frederic Becq, Ali Saleh, Andrea Pavirani, Catherine Figarella, Marc D. Merten; A cystic fibrosis tracheal gland cell line, CF-KM4. Correction by adenovirus-mediated CFTR gene transfer. Am. J. Respir. Cell Mol. Biol. 20:684-691(1999) PubMed=15463957; DOI=10.1016/j.jcf.2004.05.040 Dieter C. Gruenert, Marjolaine Willems, Jean-Jacques Cassiman, Raymond A. Frizzell; Established cell lines used in cystic fibrosis research. J. Cyst. Fibros. 3:191-196(2004)
Encyclopedic resources	Wikidata; Q54811352
Entry history
Entry creation	01-Dec-2016
Last entry update	19-Dec-2024
Version number	12