Cellosaurus cell line CFBE45o- (CVCL

Cross-references
Cell line name	CFBE45o-
Synonyms	CF45o-
Accession	CVCL_IN63
Resource Identification Initiative	To cite this cell line use: CFBE45o- (RRID:CVCL_IN63)
Comments	Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=pSVori-). Derived from site: In situ; Lung, bronchus, epithelium; UBERON=UBERON_0002031. Cell type: Epithelial cell of bronchus; CL=CL_0002328.
Sequence variations	Mutation; HGNC; HGNC:1884; CFTR; Simple; p.Arg117His (c.350G>A); ClinVar=VCV000007109; Zygosity=Heterozygous (PubMed=15463957). Mutation; HGNC; HGNC:1884; CFTR; Simple; p.Phe508del (c.1521_1523delCTT); ClinVar=VCV000007105; Zygosity=Heterozygous (PubMed=15463957).
Disease	Cystic fibrosis (NCIt: C2975) Cystic fibrosis (ORDO: Orphanet_586)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell	Sex unspecified
Age at sampling	Age unspecified
Category	Transformed cell line
Publications	PubMed=15463957; DOI=10.1016/j.jcf.2004.05.040 Dieter C. Gruenert, Marjolaine Willems, Jean-Jacques Cassiman, Raymond A. Frizzell; Established cell lines used in cystic fibrosis research. J. Cyst. Fibros. 3:191-196(2004)
Encyclopedic resources	Wikidata; Q54811429
Entry history
Entry creation	01-Dec-2016
Last entry update	19-Dec-2024
Version number	15