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Cellosaurus UOXFi004-B (CVCL_IJ08)

[Text version]
Cell line name UOXFi004-B
Synonyms iPS-OX1-19; OX1-19; iPSc clone 19 from OX1 fibroblasts; Ctrl 2#1
Accession CVCL_IJ08
Resource Identification Initiative To cite this cell line use: UOXFi004-B (RRID:CVCL_IJ08)
Comments From: University of Oxford; Oxford; United Kingdom.
Omics: Transcriptomics; Microarray.
Omics: Variations; SNP array analysis.
Derived from site: In situ; Skin, dermis; UBERON=UBERON_0002067.
Cell type: Fibroblast of skin; CL=CL_0002620.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_A8Y7 (OX1)
Sex of cell Male
Age at sampling 36Y
Category Induced pluripotent stem cell
Publications

PubMed=23951090; DOI=10.1371/journal.pone.0071098; PMCID=PMC3741356
Bonnie van Wilgenburg, Cathy Browne, Jane Vowles, Sally Anne Cowley;
Efficient, long term production of monocyte-derived macrophages from human pluripotent stem cells under partly-defined and fully-defined conditions.
PLoS ONE 8:e71098.1-e71098.18(2013)

PubMed=26905200; DOI=10.1016/j.stemcr.2016.01.013; PMCID=PMC4788783
Hugo J.R. Fernandes, Elizabeth M. Hartfield, Helen C. Christian, Evangelia Emmanoulidou, Ying Zheng, Heather Booth, Helle Bogetofte, Charmaine Lang, Brent J. Ryan, S. Pablo Sardi, Jennifer Badger ...Show all 20 authors... , Jane Vowles, Samuel Evetts, George K. Tofaris, Kostas Vekrellis, Kevin Talbot, Michele T. Hu, William S. James, Sally Anne Cowley, Richard Wade-Martins; Show fewer authors
ER stress and autophagic perturbations lead to elevated extracellular alpha-synuclein in GBA-N370S Parkinson's iPSC-derived dopamine neurons.
Stem Cell Reports 6:342-356(2016)

PubMed=28096185; DOI=10.1093/hmg/ddw412; PMCID=PMC5409122
Cynthia Sandor, Paul Robertson, Charmaine Lang, Andreas Heger, Heather Booth, Jane Vowles, Lorna Witty, Rory Bowden, Michele T. Hu, Sally Anne Cowley, Richard Wade-Martins, Caleb Webber;
Transcriptomic profiling of purified patient-derived dopamine neurons identifies convergent perturbations and therapeutics for Parkinson's disease.
Hum. Mol. Genet. 26:552-566(2017)

PubMed=30503143; DOI=10.1016/j.stem.2018.10.023; PMCID=PMC6327112
Charmaine Lang, Kieran R. Campbell, Brent J. Ryan, Phillippa J. Carling, Moustafa Attar, Jane Vowles, Olga V. Perestenko, Rory Bowden, Fahd Baig, Meike Kasten, Michele T. Hu ...Show all 14 authors... , Sally Anne Cowley, Caleb Webber, Richard Wade-Martins; Show fewer authors
Single-cell sequencing of iPSC-dopamine neurons reconstructs disease progression and identifies HDAC4 as a regulator of Parkinson cell phenotypes.
Cell Stem Cell 24:93-106.e6(2019)

Cross-references
Cell line collections (Providers) EBiSC; UOXFi004-B - Discontinued
ECACC; 66540394 - Discontinued
Cell line databases/resources hPSCreg; UOXFi004-B
Biological sample resources BioSamples; SAMEA4454111
Encyclopedic resources Wikidata; Q54991444
Gene expression databases GEO; GSM1105118
GEO; GSM1105122
Entry history
Entry creation01-Dec-2016
Last entry update10-Apr-2025
Version number12