Cellosaurus cell line UM-SCVa-1 (CVCL

Cellosaurus UM-SCVa-1 (CVCL_HX28)

Cross-references
Cell line name	UM-SCVa-1
Synonyms	UM-SCVA-1; University of Michigan-Squamous cell Carcinoma of the Vagina-1
Accession	CVCL_HX28
Resource Identification Initiative	To cite this cell line use: UM-SCVa-1 (RRID:CVCL_HX28)
Comments	Derived from site: In situ; Vagina; UBERON=UBERON_0000996.
Sequence variations	Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg248Gln (c.743G>A); ClinVar=VCV000012356; Zygosity=Unspecified (PubMed=9887230).
Disease	Vaginal squamous cell carcinoma, not otherwise specified (NCIt: C7736)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell	Female
Age at sampling	62Y
Category	Cancer cell line
Publications	PubMed=1958593; DOI=10.1002/gcc.2870030406 Bradford C.R., Kimmel K.A., Van Dyke D.L., Worsham M.J., Tilley B.J., Burk D., del Rosario F., Lutz S., Tooley R., Hayashida D.J.S., Carey T.E. 11p deletions and breakpoints in squamous cell carcinoma: association with altered reactivity with the UM-E7 antibody. Genes Chromosomes Cancer 3:272-282(1991) PubMed=7599042; DOI=10.1038/bjc.1995.289; PMCID=PMC2034151 Hietanen S.H., Grenman S.E., Syrjanen K.J., Lappalainen K., Kauppinen J., Carey T.E., Syrjanen S.M. Human papillomavirus in vulvar and vaginal carcinoma cell lines. Br. J. Cancer 72:134-139(1995) PubMed=9887230; DOI=10.1006/gyno.1998.5194 Rantanen V., Grenman S.E., Kurvinen K., Hietanen S.H., Raitanen M., Syrjanen S.M. p53 mutations and presence of HPV DNA do not correlate with radiosensitivity of gynecological cancer cell lines. Gynecol. Oncol. 71:352-358(1998)
Cell line databases/resources	cancercelllines; CVCL_HX28
Encyclopedic resources	Wikidata; Q54990968
Polymorphism and mutation databases	IARC_TP53; 10158
Entry history
Entry creation	01-Dec-2016
Last entry update	19-Dec-2024
Version number	10