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Cellosaurus MD-IGF-I (CVCL_HG41)

[Text version]
Cell line name MD-IGF-I
Accession CVCL_HG41
Resource Identification Initiative To cite this cell line use: MD-IGF-I (RRID:CVCL_HG41)
Comments Genetic integration: Method=Transfection; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR).
Genetic integration: Method=Transfection; Gene=UniProtKB; P10763; Sheep IGF1.
Genetic integration: Method=Transfection; Gene=UniProtKB; P03070; SV40 large T antigen.
Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=tsA58).
Derived from site: In situ; Mammary gland; UBERON=UBERON_0001911.
Cell type: Mammary alveolar epithelial cell; CL=CL_0002325.
Species of origin Bos taurus (Bovine) (NCBI Taxonomy: 9913)
Breed/subspecies: Holstein; VBO=VBO_0000237.
Hierarchy Parent: CVCL_U226 (MAC-T)
Sex of cell Female
Age at sampling Adult
Category Transformed cell line
Publications

PubMed=1480169; DOI=10.1210/mend.6.11.1480169
Romagnolo D., Akers R.M., Wong E.A., Boyle P.L., McFadden T.B., Turner J.D.
Overexpression of ovine insulin-like growth factor-I stimulates autonomous autocrine or paracrine growth in bovine mammary-derived epithelial cells.
Mol. Endocrinol. 6:1774-1780(1992)

Patent=US5455164
Turner J.D.
Ruminant immortalized mammary epithelial cell lines.
Patent number US5455164, 03-Oct-1995

Cross-references
Encyclopedic resources Wikidata; Q54904543
Entry history
Entry creation01-Dec-2016
Last entry update10-Apr-2025
Version number11