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Cellosaurus JEKO-1 R (CVCL_HF56)

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Cell line name JEKO-1 R
Accession CVCL_HF56
Resource Identification Initiative To cite this cell line use: JEKO-1 R (RRID:CVCL_HF56)
Comments Population: Korean.
Doubling time: 20.5 +- 1.2 hours (PubMed=26439697).
Selected for resistance to: ChEBI; CHEBI_91385; PF-00477736.
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Sequence variations
  • Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Heterozygous (from parent cell line).
  • Gene deletion; HGNC; HGNC:11998; TP53; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Pro58Glnfs*65 (c.173delC); ClinVar=VCV001394451; Zygosity=Heterozygous (from parent cell line).
Disease Mantle cell lymphoma (NCIt: C4337)
Mantle cell lymphoma (ORDO: Orphanet_52416)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1865 (JeKo-1)
Sex of cell Female
Age at sampling 78Y
Category Cancer cell line
Publications

PubMed=26439697; DOI=10.18632/oncotarget.5954; PMCID=PMC4741926
Valentina Restelli, Rosaria Chila, Monica Lupi, Andrea Rinaldi, Ivo Kwee, Francesco Bertoni, Giovanna Damia, Laura Carrassa;
Characterization of a mantle cell lymphoma cell line resistant to the Chk1 inhibitor PF-00477736.
Oncotarget 6:37229-37240(2015)

Cross-references
Encyclopedic resources Wikidata; Q54898570
Entry history
Entry creation01-Dec-2016
Last entry update19-Dec-2024
Version number14