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Cellosaurus FL5.12 Bax CL16 (CVCL_HE70)

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Cell line name FL5.12 Bax CL16
Synonyms FL5.12 Bax CL-16
Accession CVCL_HE70
Resource Identification Initiative To cite this cell line use: FL5.12 Bax CL16 (RRID:CVCL_HE70)
Comments Characteristics: IL3 dependent.
Genetic integration: Method=Transfection/transduction; Gene=MGI; MGI:99702; Bax.
Derived from site: In situ; Embryonic liver; UBERON=UBERON_0002107.
Cell type: Pro-B cell; CL=CL_0000826.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: BALB/c.
Hierarchy Parent: CVCL_0262 (FL5.12)
Sex of cell Sex unspecified
Age at sampling 13FD
Category Factor-dependent cell line
Publications

PubMed=8358790; DOI=10.1016/0092-8674(93)90509-O
Zoltan Nagy Oltvai, Curt L. Milliman, Stanley Joel Korsmeyer;
Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death.
Cell 74:609-619(1993)

PubMed=9863016; DOI=10.3892/ijo.14.1.113
Hong Zhang, Ralf Brandt, Jutta Heim, Bernd Meyhack;
Mutations in FL5.12 cells conferring resistance to apoptosis induced by interleukin-3 deprivation.
Int. J. Oncol. 14:113-120(1999)

Cross-references
Encyclopedic resources Wikidata; Q54834973
Entry history
Entry creation01-Dec-2016
Last entry update10-Sep-2024
Version number10