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Cellosaurus Bcl-x-KO MEF Bcl-xL expressing (CVCL_HC61)

[Text version]
Cell line name Bcl-x-KO MEF Bcl-xL expressing
Accession CVCL_HC61
Resource Identification Initiative To cite this cell line use: Bcl-x-KO MEF Bcl-xL expressing (RRID:CVCL_HC61)
Comments Doubling time: 24 hours (Kerafast=EUL011).
Knockout cell: Method=KO mouse; MGI; MGI:88139; Bcl2l1.
Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:992; BCL2L1 (Note=Isoform Bcl-xL).
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
Derived from site: In situ; Embryo; UBERON=UBERON_0000922.
Cell type: Fibroblast; CL=CL_0000057.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Hierarchy Parent: CVCL_HC60 (Bcl-x-KO MEF)
Sex of cell Sex unspecified
Age at sampling Embryo
Category Transformed cell line
Publications

PubMed=22573883; DOI=10.1091/mbc.E12-02-0090; PMCID=PMC3386223
Eno C.O., Eckenrode E.F., Olberding K.E., Zhao G.-P., White C., Li C.
Distinct roles of mitochondria- and ER-localized Bcl-xL in apoptosis resistance and Ca2+ homeostasis.
Mol. Biol. Cell 23:2605-2618(2012)

Cross-references
Cell line collections (Providers) Kerafast; EUL011
Encyclopedic resources Wikidata; Q54795614
Entry history
Entry creation01-Dec-2016
Last entry update19-Dec-2024
Version number10