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Cellosaurus hPOB-tert (CVCL_HA41)

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Cell line name hPOB-tert
Accession CVCL_HA41
Resource Identification Initiative To cite this cell line use: hPOB-tert (RRID:CVCL_HA41)
Comments Doubling time: 20.8 hours (PubMed=11864909).
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:11730; TERT.
Genetic integration: Method=Transduction; Gene=UniProtKB; P03070; Simian virus 40 (SV40) large T antigen.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
Derived from site: In situ; Bone, femur, periosteum; UBERON=UBERON_0016896.
Cell type: Osteoblast; CL=CL_0000062.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Sex unspecified
Age at sampling Adult
Category Transformed cell line
Publications

PubMed=11864909
Christian Darimont, Ornella Avanti, Yvonne Tromvoukis, Patricia Vautravers-Leone, Nori Kurihara, Garson David Roodman, Lorel M. Colgin, Heide Tullberg-Reinert, Andrea M.A. Pfeifer, Elizabeth A. Offord, Katherine Mace;
SV40 T antigen and telomerase are required to obtain immortalized human adult bone cells without loss of the differentiated phenotype.
Cell Growth Differ. 13:59-67(2002)

Cross-references
Encyclopedic resources Wikidata; Q54890301
Entry history
Entry creation26-Sep-2016
Last entry update14-Aug-2025
Version number10