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Cellosaurus H19-7 (CVCL_H781)

[Text version]
Cell line name H19-7
Accession CVCL_H781
Resource Identification Initiative To cite this cell line use: H19-7 (RRID:CVCL_H781)
Comments Characteristics: Grows at the permissive temperature (34 Celsius). Differentiate to a neuronal phenotype at the nonpermissive temperature (39 Celsius) when induced by FGF2.
Genetic integration: Method=Transduction; Gene=UniProtKB; P03070; SV40 large T antigen.
Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=tsA58).
Derived from site: In situ; Embryonic brain, hippocampus; UBERON=UBERON_0006238+UBERON_0002421.
Species of origin Rattus norvegicus (Rat) (NCBI Taxonomy: 10116)
Breed/subspecies: Holtzman Sprague Dawley (HotHsd:SD); RS=RS_0002942.
Hierarchy Children:
CVCL_6493 (H19-7/IGF-IR)
Sex of cell Sex unspecified
Age at sampling 17FD
Category Transformed cell line
Publications

PubMed=1316607; DOI=10.1073/pnas.89.10.4373; PMCID=PMC49084
Eves E.M., Tucker M.S., Roback J.D., Downen M., Rosner M.R., Wainer B.H.
Immortal rat hippocampal cell lines exhibit neuronal and glial lineages and neurotrophin gene expression.
Proc. Natl. Acad. Sci. U.S.A. 89:4373-4377(1992)

PubMed=10786694
Morrione A., Romano G., Navarro M., Reiss K., Valentinis B., Dews M., Eves E.M., Rosner M.R., Baserga R.
Insulin-like growth factor I receptor signaling in differentiation of neuronal H19-7 cells.
Cancer Res. 60:2263-2272(2000)

Cross-references
Cell line collections (Providers) ABM; T0359
Encyclopedic resources Wikidata; Q54871971
Experimental variables resources EFO; EFO_0022832
Entry history
Entry creation11-Feb-2013
Last entry update10-Apr-2025
Version number14