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Cellosaurus DLKP-A2B (CVCL_H744)

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Cell line name DLKP-A2B
Accession CVCL_H744
Resource Identification Initiative To cite this cell line use: DLKP-A2B (RRID:CVCL_H744)
Comments Selected for resistance to: ChEBI; CHEBI_28748; Doxorubicin (Adriablastin; Adriamycin).
Donor information: Established from a patient that smoked approximately 40 cigarettes a day for most of his adult life (from parent cell line).
Derived from site: Metastatic; Lymph node; UBERON=UBERON_0000029.
Disease Lung squamous cell carcinoma (NCIt: C3493)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_H741 (DLKP-A)
Sex of cell Male
Age at sampling 52Y
Category Cancer cell line
Publications

PubMed=9180164; DOI=10.1002/(SICI)1097-0215(19970529)71:5<907::AID-IJC33>3.0.CO;2-1
Mary Heenan, Lorraine O'Driscoll, Irene Cleary, Lisa Connolly, Martin Clynes;
Isolation from a human MDR lung cell line of multiple clonal subpopulations which exhibit significantly different drug resistance.
Int. J. Cancer 71:907-915(1997)

PubMed=19242932; DOI=10.1002/pmic.200800633
Joanne Keenan, Lisa Murphy, Michael Henry, Paula Meleady, Martin Clynes;
Proteomic analysis of multidrug-resistance mechanisms in adriamycin-resistant variants of DLKP, a squamous lung cancer cell line.
Proteomics 9:1556-1566(2009)

Cross-references
Encyclopedic resources Wikidata; Q54831179
Entry history
Entry creation11-Feb-2013
Last entry update14-Aug-2025
Version number12