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Cellosaurus Mac-1 (CVCL_H631)

[Text version]
Cell line name Mac-1
Synonyms MAC-1; MAC1; McG-1
Accession CVCL_H631
Resource Identification Initiative To cite this cell line use: Mac-1 (RRID:CVCL_H631)
Comments Omics: Transcriptomics; RNAseq.
Donor information: Originally the patient was suffering from Hodgkin lymphoma.
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Cell type: T-cell; CL=CL_0000084.
Disease Primary cutaneous T-cell non-Hodgkin lymphoma (NCIt: C3467)
Primary cutaneous T-cell lymphoma (ORDO: Orphanet_171901)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_H632 ! Mac-2
Sex of cell Male
Age at sampling 45Y
Category Cancer cell line
Publications

CLPUB00077
Marshall Edward Kadin, Dianne Sako, Cynthia Casson Morton, Samuel R. Newcom, Ih-Jen Su;
Characterization of a neoplastic T cell line from a patient with cutaneous T cell lymphoma and regressing T cell skin lesions.
Lab. Invest. 58:45A-45A(1988)

PubMed=2456698; PMCID=PMC1880737
Ih-Jen Su, Steven Paul Balk, Marshall Edward Kadin;
Molecular basis for the aberrant expression of T cell antigens in postthymic T cell malignancies.
Am. J. Pathol. 132:192-198(1988)

PubMed=2898211; PMCID=PMC1880714
Samuel R. Newcom, Marshall Edward Kadin, Aftab A. Ansari;
Production of transforming growth factor-beta activity by Ki-1 positive lymphoma cells and analysis of its role in the regulation of Ki-1 positive lymphoma growth.
Am. J. Pathol. 131:569-577(1988)

PubMed=1532439; DOI=10.1056/NEJM199204233261704
Thomas H. Davis, Cynthia Casson Morton, Robert Miller-Cassman, Steven Paul Balk, Marshall Edward Kadin;
Hodgkin's disease, lymphomatoid papulosis, and cutaneous T-cell lymphoma derived from a common T-cell clone.
N. Engl. J. Med. 326:1115-1122(1992)

PubMed=9162223; DOI=10.1006/cyto.1996.0044
Rosa M. Marti, Mariusz A. Wasik, Marshall Edward Kadin;
Constitutive secretion of GM-CSF by three different cell lines derived from a single patient with a progressive cutaneous lymphoproliferative disorder.
Cytokine 8:323-329(1996)

DOI=10.1016/B978-0-12-221970-2.50457-5
Hans Gunther Drexler;
The leukemia-lymphoma cell line factsbook.
(In book) ISBN 9780122219702; pp.1-733; Academic Press; London; United Kingdom (2001)

PubMed=28356514; DOI=10.1073/pnas.1700682114; PMCID=PMC5393253
Jing Chen, Yong Zhang, Michael N. Petrus, Wen-Ming Xiao, Alina Nicolae, Mark Raffeld, Stefania Pittaluga, Richard N. Bamford, Masao Nakagawa, Sunny Tian-Yi Ouyang, Alan L. Epstein ...Show all 16 authors... , Marshall Edward Kadin, Annarose Del Mistro, Richard D. Woessner, Elaine Sarkin Jaffe, Thomas Alexander Waldmann; Show fewer authors
Cytokine receptor signaling is required for the survival of ALK- anaplastic large cell lymphoma, even in the presence of JAK1/STAT3 mutations.
Proc. Natl. Acad. Sci. U.S.A. 114:3975-3980(2017)

PubMed=29533902; DOI=10.1515/hsz-2017-0321
Hans Gunther Drexler, Claudia Pommerenke, Sonja Eberth, Stefan Nagel;
Hodgkin lymphoma cell lines: to separate the wheat from the chaff.
Biol. Chem. 399:511-523(2018)

Cross-references
Cell line databases/resources cancercelllines; CVCL_H631
Cell_Model_Passport; SIDM01369
Anatomy/cell type resources BTO; BTO_0004869
Encyclopedic resources Wikidata; Q54903946
Gene expression databases GEO; GSM1217151
GEO; GSM2527945
Polymorphism and mutation databases Cosmic; 2013355
Cosmic; 2674499
Cosmic; 2814456
Progenetix; CVCL_H631
Entry history
Entry creation11-Feb-2013
Last entry update10-Apr-2025
Version number19