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Cellosaurus TRAMP-C1A (CVCL_H593)

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Cell line name TRAMP-C1A
Synonyms TRAMP.C1A; TRAMP C1A; C1A
Accession CVCL_H593
Resource Identification Initiative To cite this cell line use: TRAMP-C1A (RRID:CVCL_H593)
Comments Genetic integration: Method=Transgenic mouse; Gene=UniProtKB; P03070; Simian virus 40 (SV40) large T antigen.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
Derived from site: In situ; Prostate; UBERON=UBERON_0002367.
Disease Carcinoma of the mouse prostate gland (NCIt: C21732)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: C57BL/6-TgN(TRAMP)8247Ng.
Hierarchy Parent: CVCL_3614 (TRAMP-C1)
Sex of cell Male
Age at sampling 32W
Category Cancer cell line
Publications

PubMed=11063747; DOI=10.1074/jbc.M008207200
Guang-Zhou Han, Barbara A. Foster, Sandeep Mistry, Grant Buchanan, Jonathan M. Harris, Wayne Desmond Tilley, Norman M. Greenberg;
Hormone status selects for spontaneous somatic androgen receptor variants that demonstrate specific ligand and cofactor dependent activities in autochthonous prostate cancer.
J. Biol. Chem. 276:11204-11213(2001)

PubMed=14559809
Kevin W. Freeman, Rama D. Gangula, Bryan E. Welm, Mustafa Ozen, Barbara A. Foster, Jeffrey M. Rosen, Michael Ittmann, Norman M. Greenberg, David M. Spencer;
Conditional activation of fibroblast growth factor receptor (FGFR) 1, but not FGFR2, in prostate cancer cells leads to increased osteopontin induction, extracellular signal-regulated kinase activation, and in vivo proliferation.
Cancer Res. 63:6237-6243(2003)

Cross-references
Chemistry resources ChEMBL-Cells; CHEMBL3307772
ChEMBL-Targets; CHEMBL614367
PubChem_Cell_line; CVCL_H593
Encyclopedic resources Wikidata; Q54972947
Entry history
Entry creation11-Feb-2013
Last entry update14-Aug-2025
Version number12