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Cellosaurus BRI-JM04 (CVCL_H219)

[Text version]
Cell line name BRI-JM04
Accession CVCL_H219
Resource Identification Initiative To cite this cell line use: BRI-JM04 (RRID:CVCL_H219)
Comments Characteristics: Can be used to investigate Neu oncogene driven mammary tumorigenesis (PubMed=15318933).
Doubling time: 22 hours (PubMed=15318933).
Genetic integration: Method=Transgenic mouse; Gene=RGD; 2561; Erbb2 (Note=With p.Val661Glu).
Transformant: Activated Erbb2/neu.
Derived from site: In situ; Mammary gland; UBERON=UBERON_0001911.
Disease Malignant neoplasms of the mouse mammary gland (NCIt: C21678)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: FVB MMTV/activated Neu.
Sex of cell Female
Category Cancer cell line
Publications

PubMed=15318933; DOI=10.1186/bcr907; PMCID=PMC549171
Lenferink A.E.G., Magoon J., Cantin C., O'Connor-McCourt M.D.
Investigation of three new mouse mammary tumor cell lines as models for transforming growth factor (TGF)-beta and Neu pathway signaling studies: identification of a novel model for TGF-beta-induced epithelial-to-mesenchymal transition.
Breast Cancer Res. 6:R514-R530(2004)

Cross-references
Encyclopedic resources Wikidata; Q54798234
Entry history
Entry creation11-Feb-2013
Last entry update19-Dec-2024
Version number7