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Cellosaurus FO1-12 (CVCL_GZ38)

[Text version]
Cell line name FO1-12
Synonyms Fo1-12; FO-1 #12
Accession CVCL_GZ38
Resource Identification Initiative To cite this cell line use: FO1-12 (RRID:CVCL_GZ38)
Comments Group: Patented cell line.
Registration: International Depositary Authority, American Type Culture Collection (ATCC); CRL-12177.
Population: Caucasian.
Selected for resistance to: ChEBI; CHEBI:9555; Tioguanine (6-thioguanine; 6-TG).
Transfected with: UniProtKB; P00552; Transposon Tn5 neo.
Transformant: NCIt; C44386; Gamma radiation.
Derived from site: Metastatic; Iliac lymph node; UBERON=UBERON_0015878.
Sequence variations
  • Mutation; HGNC; 1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Unspecified (from parent cell line).
Disease Amelanotic melanoma (NCIt: C3802)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_5619 (MEL-CLS-1)
Sex of cell Female
Age at sampling 54Y
Category Cancer cell line
Publications

Patent=US6063375
Gattoni-Celli S., Newton D.A. III, McClay E.F.
Semiallogeneic cell hybrids and related methods for treating cancer.
Patent number US6063375, 16-May-2000

PubMed=10746551; DOI=10.1097/00002371-200003000-00009
Newton D.A. III, Romano C., Gattoni-Celli S.
Semiallogeneic cell hybrids as therapeutic vaccines for cancer.
J. Immunother. 23:246-254(2000)

PubMed=10983636; DOI=10.1097/00002030-200007280-00005
Grene E., Newton D.A. III, Brown E.A., Berzofsky J.A., Gattoni-Celli S., Shearer G.M.
Semi-allogeneic cell hybrids stimulate HIV-1 envelope-specific cytotoxic T lymphocytes.
AIDS 14:1497-1506(2000)

Cross-references
Cell line databases/resources cancercelllines; CVCL_GZ38
TOKU-E; 3586
Encyclopedic resources Wikidata; Q54835102
Entry history
Entry creation26-Sep-2016
Last entry update05-Oct-2023
Version number12